丛集性头痛中炎性小体复合物的表达降低

Headache: The Journal of Head and Face Pain Pub Date : 2022-06-07 DOI:10.1111/head.14334

Erdi Şahin, Z. Karaaslan, E. Şanlı, Özlem Tımırcı Kahraman, C. Ulusoy, Elif Kocasoy Orhan, E. Ekizoğlu, C. Küçükali, E. Tüzün, B. Baykan

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引用次数: 0

摘要

炎症参与丛集性头痛(CH)的病理生理，暗示了白细胞介素(IL)‐1β的作用。我们旨在测量IL - 1β诱导系统、炎性小体复合物和活化B细胞(NF - κB)信号的核因子κ轻链增强子的外周血表达水平，并研究它们作为CH推定生物标志物的价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Reduced expression of inflammasome complex components in cluster headache

The involvement of inflammation in the pathophysiology of cluster headache (CH) has been suggested, with a role implied for interleukin (IL)‐1β. We aimed to measure peripheral blood expression levels of IL‐1β–inducing systems, the inflammasome complex, and nuclear factor kappa‐light‐chain‐enhancer of activated B cells (NF‐κB) signaling, and investigate their values as putative biomarkers in CH.

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Headache: The Journal of Head and Face Pain

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