洋甘菊提取物对胃周皮肤并发症的预防作用

A. Abedi, M. Dianati, H. Gilasi
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引用次数: 0

摘要

目的:本研究的目的是确定洋甘菊提取物对预防肠周皮肤并发症的作用。方法:这项单盲、安慰剂对照、随机临床试验对伊朗伊斯法罕Koroush健康诊所的80例造口患者进行了研究。对于干预组的参与者,洋甘菊提取物被局部应用于肠周皮肤。对于对照组的参与者,使用蒸馏水作为安慰剂。干预组参与者使用造口皮肤工具(OST)检查口周皮肤,每周一次,连续四周。在研究开始和结束时对对照组的口周皮肤进行评估。结果:干预组与对照组在性别、婚姻状况、文化程度、造口类型、化疗史、放疗史等方面差异无统计学意义。OST评分显示,干预后对照组造口周围皮肤并发症(颜色变化、分泌物、创面)评分明显高于干预组(P < 0.05)。结论:洋甘菊提取物可有效预防肠周皮肤并发症及相关副作用。本研究的结果可被卫生保健专业人员用于处理肠周皮肤并发症。
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Effect of Chamomile Extract on Prevention of Peristomal Skin Complications
Objectives: The purpose of the present study was to determine the effect of chamomile extract on the prevention of peristomal skin complications. Methods: This single-blinded, placebo-controlled, randomized clinical trial was conducted on 80 ostomy patients who were referred to Koroush Health Clinic, Isfahan, Iran. For the participants in the intervention group, chamomile extract was applied topically on the peristomal skin. For the participants in the control group, distilled water was applied as a placebo. The intervention group participants’ peristomal skin was examined using the ostomy skin tool (OST) once a week for four consecutive weeks. The peristomal skin in the control group was assessed at the beginning and the end of the study. Results: The intervention and control groups were not significantly different in terms of gender, marital status, educational degree, ostomy type, chemotherapy history, and radiotherapy history. The scores of the OST indicated that after the intervention, the scores of skin complications (color change, secretion, and wound) around the stoma were significantly higher in the control group than in the intervention group (P < 0.05). Conclusions: Our findings showed that chamomile extract was effective in preventing peristomal skin complications and related side effects. The results of the present study can be used by health care professionals to manage peristomal skin complications.
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