BCGitis引起的局部脓肿

IF 0.1 Q4 PEDIATRICS Journal of Pediatric Infection Pub Date : 2022-12-14 DOI:10.5578/ced.20229615
E. Çiftçi, Hatice Belkıs İnceli, H. Özdemir, Şule Haskoloğlu, F. Doğu
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引用次数: 0

摘要

一名8个月大的女婴因接种卡介苗的部位肿胀加剧而入院。据了解,卡介苗是在两个月大的时候接种的。随着时间的推移,接种区域出现肿胀并逐渐增大。母亲和父亲之间没有血缘关系。母亲的一个兄弟姐妹在一岁时失去了,原因不明。病人体温正常。检查时,在接种卡介苗的左三角肌区观察到直径约3cm的红肿和波动肿胀。其他体格检查结果正常。检查后不久脓肿就自发地流脓了。引流液中结核分枝杆菌复合体PCR阳性。从卡介苗中分离出的牛分枝杆菌对异烟肼和利福平敏感。免疫检查血清IgG、IgM水平低的患儿淋巴细胞亚群、淋巴细胞活化反应、爆发试验及IL-12rβ1表达均正常。基因研究计划针对其他易患分枝杆菌疾病的免疫缺陷。患者开始使用异烟肼和利福平治疗。病人的病变,其治疗方法是
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Local abscess due to BCGitis
An eight-month-old girl was brought in because of increasing swelling in the area where the BCG vaccine was given. It was learned that the BCG vaccine was administered at the age of two months. Over time, there was swelling in the vaccination area and gradually increased. There was no consanguinity be-tween mother and father. A sibling of the mother was lost at the age of one, for unknown reasons. The patient’s body tem-perature was normal. On examination, redness and fluctuating swelling with a diameter of about 3 cm was observed in the left deltoid region, where BCG vaccination was administered. Other physical examination findings of the patient were normal. The abscess drained spontaneously shortly after examination. Mycobacterium tuberculosis complex PCR was positive in the drainage material. The strain evaluated to be Mycobacterium bovis from the BCG vaccine was susceptible to isoniazid and rifampin. Lymphocyte subgroups, lymphocyte activation response, burst test and IL-12rβ1 expression were normal in the child with low serum IgG and IgM levels in immunologi-cal tests. Genetic study was planned in terms of other immu-nodeficiencies that predispose to mycobacterial diseases. The patient was started on isoniazid and rifampin treatment. The lesion of the patient, whose treatment was
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