金合欢注射液的一些药理性质

O. Barnaulov
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摘要

背景:Chamerion angustifolium作为茶的替代品和一种温和的镇静剂已经在人们中流行了几个世纪。叶子冲剂用于神经症、头痛、癫痫和其他神经系统疾病。目的:通过实验验证龙舌兰叶冲剂的脑保护作用。方法:采用最大电击法、条件被动回避法和固定应激法对大鼠和小鼠进行实验。结果:实验结果显示,叶滴注无抗惊厥作用。脑保护作用表现在最大休克后被动回避条件反射的保留和探索行为的更快恢复。小鼠在固定应激过程中表现出明显的应力限制特性。发酵过的叶子已被证明不如未发酵过的叶子有效。结论:本研究证实了金合欢注射液具有一定的脑保护作用。
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Some pharmacological propertyes of Chamerion angustifolium infusions
BACKGROUND: Chamerion angustifolium has been popular among the people for many centuries as a substitute for tea and a mild sedative. Leaf infusions are used for neurosis, cephalgia, epilepsy and other neurological diseases. AIM: Was to experimentally confirm the cerebroprotective properties of Chamerion leaf infusions. METHODS: We used the methods of maximum electric shock, conditioned passive avoidance, and immobilization stress in rats and mice. RESULTS: Infusions of leaves experimentally revealed no anticonvulsant properties. Cerebroprotective properties were manifested in the preservation of the passive avoidance conditioned reflex after maximum shock and faster recovery of exploratory behavior. Distinct stress-limiting properties were revealed during immobilization stress in mice. Fermented leaves have been shown to be less effective than non-fermented ones. CONCLUSION: The data obtained confirm the presence of cerebroprotective properties of the infusion of Chamerion angustifolium.
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