To Study the Effect of Laparoscopic Sleeve Gastrectomy on BMI and Metabolic Parameters in Morbidly Obese Patients

Introduction: Obesity for centuries has had myriad implications on physical, mental, and psychosocial health. Various therapies like nutritional therapy, physical activity, pharmacotherapy, and cognitive-behavioral therapy have failed in managing obesity and lead to disappointing results. Contrary to these results, bariatric surgery has shown to have a decrease in weight of 50–75%. Not only has bariatric surgery been effective in morbid obesity but it also plays a significant role in a high rate of remission of type 2 diabetes mellitus and other obesity-related comorbidities like dyslipidemia, hypertension, and obstructive sleep apnea (OSA) syndrome. Materials and methods: This is a prospective study, undertaken in Mahatma Gandhi Medical College and Hospital, Jaipur, from July 2017 to September 2019 after taking clearance from the Institution ethics committee. A total of 30 patients were included in this study who were morbidly obese with metabolic syndrome. The indications for surgery were according to the latest guidelines issued by the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) for the Asian population. Results: There was a significant fall in all parameters like weight, body mass index (BMI), fasting blood sugar (FBS), HbA1c, hypertension, and dyslipidemia. The weight loss and BMI baseline were seen by the end of 12 months were 40 ± 9.3 kg and from 43.23 to 29.75, respectively, showing its statistical significance. There was a substantial decrease in baseline fasting sugar from 172 ± 19.7 to 139 ± 17.2 mg/dL. Simultaneously, a fall in HbA1c values was seen from the mean of 8.67 ± 1.1 to 6.18 ± 0.4 at the end of 1 year. There is a noteworthy improvement seen in hypertension by the end of 3rd month with mean systolic coming down to 131 ± 14 mm Hg and diastolic to 77 ± 11 mm Hg. Dyslipidemia seen in 21 patients out of 30 patients saw a 100% improvement. Therefore, laparoscopic sleeve gastrectomy (LSG) plays a vital role in reducing morbidity and mortality by effective weight loss and control of comorbid diseases.