化学交联聚乙烯醇/明胶伤口敷料加载姜黄素

E. Kenawy, Abdelbaset Shoker, Zeinab S. Ghaly, M. A. El-Meligy
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引用次数: 0

摘要

伤口敷料是治疗慢性伤口感染的迫切需要。本研究旨在制备化学交联dpva和明胶聚合物组成的膜。加入姜黄素改善膜的生物学性能。利用红外光谱(FTIR)对其化学结构进行了表征,利用扫描电镜(SEM)和热重分析(TGA)对交联膜的形貌和热性能进行了研究。此外,还进行了接触角测量,以获得更多的物理化学性质信息。此外,还进行了生物降解性研究,结果表明制备的可生物降解PVA/明胶/姜黄素膜可以有效地用作伤口愈合的敷料。
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Chemically Crosslinked Polyvinyl Alcohol/ Gelatin Wound Dressing Loaded With Curcumin
Wound dressings are highly desired for the treatment of chronic wound infections. This study aimed to prepare membranes composed of chemically crosslinkedPVA and Gelatin polymers. Curcumin was added to improve the membrane's biological properties. FTIR spectroscopy was used to investigate their chemical structures, while SEM and TGA analysis were applied to studies the morphology of the membrane and the thermal properties of the crosslinked membranes. In addition, the contact angle measurement was also performed to get more information about the physicochemical properties. In addition, the biodegradability studies were performed and the findings highlighted that the prepared biodegradable PVA/ Gelatin/ Curcumin membranes could be efficiently used as dressers for enhancing wound healing.
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