全耳重建的框架:过去,现在和未来的方向

Luke B Soliman, M. Borrelli, Nikhil Sobti, A. Woo
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引用次数: 2

摘要

全耳重建术描述了旨在修复外耳以纠正获得性或先天性畸形的手术方法。在过去的一个世纪里,耳廓重建的框架经历了实质性的发展,在本质上大致分为自体和同种异体。最近,组织工程、再生医学和材料科学的进步为通过开发来自患者自身细胞的尖端3D结构(称为生物打印)来重建耳朵的软骨和软组织结构开辟了新的途径。本综述概述了耳部重建框架的历史方法,并提供了当前生物打印工作的最新摘要和评价。
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Frameworks for total ear reconstruction: past, present and future directions
Total ear reconstruction describes surgical approaches aimed toward restoring the external ear to correct acquired or congenital deformities. Frameworks for auricular reconstruction have undergone substantial evolution over the past century and are broadly categorized as either autologous or alloplastic in nature. Recently, advances in tissue engineering, regenerative medicine and materials science have opened new avenues for recreating the cartilaginous and soft tissue structures of the ear through development of cutting-edge 3D constructs derived from a patient's own cells in a process known as bioprinting. This review outlines the historical approaches to frameworks for ear reconstruction and provides an updated synopsis and appraisal of current bioprinting efforts.
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CiteScore
2.70
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0.00%
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