肾移植后下尿路症状的流行及其尿动力学特征

Putri Iradita Islianti, H. Rahardjo, N. Rasyid, A. Rodjani
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摘要

目的:本研究旨在描述肾移植后LUTS患者行尿动力学检查的尿动力学特征。材料与方法:本研究是2011-2017年在Cipto Mangunkusumo总医院进行的横断面研究。数据收集于因LUTS/尿潴留而接受肾移植后尿动力学检查的患者。数据是从病人的医疗记录中收集的。结果:2011-2017年,共有536例患者在Cipto Mangunkusumo总医院接受肾脏移植手术。11例(2%)患者发生LUTS后行尿动力学检查,平均年龄41.4(30.1±52.6)岁。2型糖尿病(DM) 6例(55%),高血压(HT) 5例(45%)。11例患者中有6例(54%)出现尿潴留,其中4例(67%)出现膀胱依从性下降,4例(67%)出现逼尿肌过度活动(DO), 3例(50%)出现膀胱出口梗阻(BOO), 2例(33%)出现逼尿肌活动不足(DU)。在5例无尿潴留的患者中,1例患者膀胱顺应性下降(20%),2例患者DO(40%), 1例患者BOO(20%),没有受试者经历DU。在两组中,没有发现受试者出现任何尿失禁。结论:肾移植后发生LUTS的患者较少,其中半数患者伴有尿潴留。在这些患者中,尿动力学检查显示逼尿肌过度活动是最常见的潜在问题,其次是膀胱顺应性降低、BOO和逼尿肌活动不足
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PREVALENCE OF LOWER URINARY TRACT SYMPTOMS POST KIDNEY TRANSPLANTATION AND ITS URODYNAMIC PROFILE
Objective: This study aimed to describe the urodynamic characteristics of post-transplant kidney patients with LUTS who were indicated for urodynamics. Material & Methods: This research is a cross-sectional study conducted at Cipto Mangunkusumo General Hospital between 2011-2017. Data were collected from patients who had undergone urodynamic examination after kidney transplantation due to LUTS/urinary retention. Data were collected from the patient’s medical record. Results: A total of 536 patients underwent kidney transplants at Cipto Mangunkusumo General Hospital from 2011-2017. Eleven patients (2%) developed LUTS and then underwent urodynamic examination with an average age of 41.4 (30.1 ± 52.6) years. Six patients (55%) had type 2 diabetes mellitus (DM) and 5 patients (45%) had hypertension (HT). A total of 6 out of 11 patients (54%) experienced urinary retention of which 4 subjects (67%) had decreased bladder compliance, 4 (67%) patients experienced detrusor overactivity (DO), 3 patients (50%) had bladder outlet obstruction (BOO), while 2 patients (33%) experienced detrusor underactivity (DU) respectively. Of 5 patients without urinary retention, decreased bladder compliance was found in 1 patient (20%), DO in 2 patients (40%), BOO in 1 patient (20%), and no subject experienced DU. In both groups, no subject was discovered to experience any urinary incontinence. Conclusion: Small number of post renal transplantation patients developed LUTS and half of which accompanied by urinary retention. Among these patients, urodynamic examination revealed detrusor overactivity as the most common underlying problem followed by decreased bladder compliance, BOO, and detrusor underactivity
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