免疫性血小板减少性紫癜:一例罕见的术后血小板减少症

V. Thomas, S. Rao
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摘要

一例免疫性血小板减少性紫癜(ITP)是一例罕见的术后出血病例。我们的病人提出了一个选择性腹腔镜全腹膜外修补腹股沟疝。他接受了手术,没有手术或立即的术后并发症。术后第1天,患者出现心动过速并低血压,临床检查显示面色苍白,有瘀点和瘀斑。全血细胞计数显示血小板减少伴正红细胞性贫血,而凝血参数正常。血清生化未发现任何肾功能衰竭或乳酸脱氢酶升高。计算机断层扫描和血管造影显示支持腹膜出血的特征。我们的病人首先通过输血和血管加压药物支持稳定下来。骨髓分析显示ITP的特征,但二次检查仍为阴性。我们的患者使用地塞米松脉冲治疗,随后使用维持性类固醇,随后血小板计数出现增量反应。
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Immune thrombocytopenic purpura: A rare case of postoperative thrombocytopenia
A case of Immune Thrombocytopenic Purpura (ITP) presented as an unusual case of post- operative hemorrhage. Our patient had presented for an elective laparoscopic total extraperitoneal repair for an inguinal hernia. He had undergone the procedure with no procedural or immediate post- operative complications. On post- op day 1, our patient had developed tachycardia with hypotension with clinical examination revealing signs of pallor with petechiae and ecchymosis. A complete blood count revealed thrombocytopenia with normocytic anemia while coagulation parameters were normal. Serum biochemistries did not reveal any renal failure or elevated lactate dehydrogenase. A computer- tomography with angiography revealed features supportive of a hemoperitoneum. Our patient was first stabilized with transfusion and vasopressor support. Evaluation with bone marrow analysis revealed features suggestive of ITP while secondary workup remained negative. Our patient was managed with dexamethasone pulse followed by maintenance steroids, following which there was an incremental response of the platelet count.
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