个性化医疗的伦理

Jack Kushner MD, MGA, FACS, FICS, FAANS, HDG
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引用次数: 5

摘要

个性化医疗是医学的一个分支,病人的治疗和预后是基于他的基因。最近的基因研究解释了人类之间的差异和相似之处,他们的疾病,以及他们对各种治疗的反应。由于政府和大学没有制定严格的标准,有许多测试和试剂盒可用于检测遗传问题。但是这些工具准确吗?一些生物标记物的有效性值得怀疑。当一些实验室测试导致女性被错误地告知她们患乳腺癌或卵巢癌的风险很高时,个性化医疗的伦理就成了一个问题。伦理问题不仅限于遗传信息的利用,而且可以在获取人类材料以提高知识的过程中提出。这些是谁的基因?谁拥有你的DNA?在美国,患者会得到产前遗传建议,他们可以自行决定如何进行。但在俄罗斯,病人别无选择。国家做出了大部分决定。选择性育种在西方国家是不可接受的。
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The ethics of personalized medicine

Personalized medicine is that branch of medicine whereby a patient's treatment and prognosis are based on his genes. Recent genetic research explains the variations and similarities between humans, their diseases, and their responses to various treatments. Because governments and universities have not set strict standards, there are numerous tests and kits available to detect genetic problems. But are these kits accurate? The validity of some biomarkers is suspect.

The ethics of personalized medicine became an issue when some laboratory tests resulted in women incorrectly having been told that they have a high risk of breast or ovarian cancer when they did not. Ethical issues are not confined to the utilization of genetic information, but can be raised with the acquisition of human material for the advancement of knowledge. Whose genes are these? Who owns your DNA?

In the US, patients are given prenatal genetic advice upon which they can decide for themselves how to proceed. But in Russia, patients have no choice. The state makes most decisions. Selective breeding would be unacceptable in western countries.

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