{"title":"转化生长因子-?1、不孕不育","authors":"Suaad Hilal","doi":"10.32792/utq/utjsci/v10i1.1050","DOIUrl":null,"url":null,"abstract":"Abstract: Male infertility is a problem that affects 10–15% of men in reproductive age. The present study aimed to detect the role Transforming Growth Factor-?1 (TGF-?1) cytokine in infertility outpatients’ males at Al-Nasiriya Educational Hospital / Infertility Unit / Thi-Qar Governorate Iraq, during the period from September 2022 to March 2023. Serum samples from 88 (76 infertility males and 12 control) were collected and assayed by Sandwich-ELISA technique. Infertility patients were distributed to Primary and secondary infertility type with a 66(86.84%) and 10(13.016%) patient, respectively (P?0.01). All infertility patients showed an elevated mean sera levels of TGF-?1 with (0.734±0.45 pg/ml), as compared with the controls (0.670± 0.393 pg/ml). No statistical differences were appeared between the two groups included in the present study regarding this cytokine (P>0.05). The study results may shed light the role of TGF-?1 as a serological tool in male infertility. ","PeriodicalId":23432,"journal":{"name":"University of Thi-Qar Journal of Science","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Transforming Growth Factor-?1 and infertility\",\"authors\":\"Suaad Hilal\",\"doi\":\"10.32792/utq/utjsci/v10i1.1050\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract: Male infertility is a problem that affects 10–15% of men in reproductive age. The present study aimed to detect the role Transforming Growth Factor-?1 (TGF-?1) cytokine in infertility outpatients’ males at Al-Nasiriya Educational Hospital / Infertility Unit / Thi-Qar Governorate Iraq, during the period from September 2022 to March 2023. Serum samples from 88 (76 infertility males and 12 control) were collected and assayed by Sandwich-ELISA technique. Infertility patients were distributed to Primary and secondary infertility type with a 66(86.84%) and 10(13.016%) patient, respectively (P?0.01). All infertility patients showed an elevated mean sera levels of TGF-?1 with (0.734±0.45 pg/ml), as compared with the controls (0.670± 0.393 pg/ml). No statistical differences were appeared between the two groups included in the present study regarding this cytokine (P>0.05). The study results may shed light the role of TGF-?1 as a serological tool in male infertility. \",\"PeriodicalId\":23432,\"journal\":{\"name\":\"University of Thi-Qar Journal of Science\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-06-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"University of Thi-Qar Journal of Science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32792/utq/utjsci/v10i1.1050\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"University of Thi-Qar Journal of Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32792/utq/utjsci/v10i1.1050","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Abstract: Male infertility is a problem that affects 10–15% of men in reproductive age. The present study aimed to detect the role Transforming Growth Factor-?1 (TGF-?1) cytokine in infertility outpatients’ males at Al-Nasiriya Educational Hospital / Infertility Unit / Thi-Qar Governorate Iraq, during the period from September 2022 to March 2023. Serum samples from 88 (76 infertility males and 12 control) were collected and assayed by Sandwich-ELISA technique. Infertility patients were distributed to Primary and secondary infertility type with a 66(86.84%) and 10(13.016%) patient, respectively (P?0.01). All infertility patients showed an elevated mean sera levels of TGF-?1 with (0.734±0.45 pg/ml), as compared with the controls (0.670± 0.393 pg/ml). No statistical differences were appeared between the two groups included in the present study regarding this cytokine (P>0.05). The study results may shed light the role of TGF-?1 as a serological tool in male infertility.
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