The Hidden Ingredients Affecting Cancer Patients Outcome and the Mathematical Journey to Their Uncover

2) Basic biology events of normal cycling cells [5], and principals involved in cancer pathogenesis named "hallmarks of cancer," including sustaining proliferative signaling, evading growth suppressors, resisting cell death, enabling replicative immortality, angiogenesis, activating invasion and metastasis, and recently expanded to include also reprogramming of energy metabolism and evading immune destruction [6,7];