社会人口学因素与雌激素受体阳性、孕激素受体阳性乳腺癌亚型之间的关系:一项横断面研究

IF 0.3 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Makara Journal of Health Research Pub Date : 2020-08-25 DOI:10.7454/msk.v24i2.1213
Vinodkumar Mugada, R. Kolakota, Varsha Mahato
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引用次数: 0

摘要

背景:存在高危因素的人患乳腺癌的风险较高。我们的研究旨在发现社会人口学因素与女性雌激素受体(ER)阳性、孕激素受体(PR)阳性乳腺癌风险之间的关系。方法:对200例乳腺癌患者进行横断面研究。使用Chisquare检验发现社会人口学因素与乳腺癌激素受体亚型之间存在关联。采用多元logistic回归分析了解激素受体亚型的强预测因子。结果:患者平均年龄为50.08(10.67)岁。合并症与er阳性亚型的相关性有统计学意义(p = 0.007)。体重指数与pr阳性亚型有统计学意义(p = 0.042)。合并症是er阳性的独立预测因子(OR 2.28;95% CI: 1.28-4.05, p = 0.01)和pr阳性亚型(OR 1.78;95% CI: 1.01-3.13, p = 0.03)。结论:在我们的研究中,体重指数与pr阳性亚型相关,合并症与er阳性亚型乳腺癌相关。合并症仍然是雌激素受体阳性和雌激素受体阳性乳腺癌亚型的一个强有力的独立预测因子。
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Association between sociodemographic factors and estrogen receptor-positive, progesterone receptor-positive breast cancer subtypes: A cross-sectional study
Background: The presence of risk factors have a high risk of developing breast cancer. Our study aimed to find an association between sociodemographic factors and the risk of estrogen receptor (ER)-positive, progesterone receptor (PR)positive breast cancer among women. Methods: A cross-sectional study was conducted on 200 women with breast cancer. Association between sociodemographic factors and hormone receptor subtypes of breast cancer was found using the Chisquare test. Multiple logistic regression analysis was used to know the strong predictors of hormone receptor subtypes. Results: The mean age was 50.08 (10.67) years. Comorbidities had a statistically significant association with ER-positive subtype (p = 0.007). Body mass index had a statistically significant association with PR-positive subtype (p = 0.042). Comorbidities was found to be the strong independent predictor for ER-positive (OR 2.28; 95% CI: 1.28–4.05, p = 0.01) and PR-positive subtypes (OR 1.78; 95% CI: 1.01–3.13, p = 0.03). Conclusion: We conclude that in our study, body mass index was associated with PR-positive subtype, and comorbidities were associated with ER-positive subtype of breast cancer among the women. Comorbidities remained to be a strong independent predictor of ER-positive and PRpositive subtypes of breast cancer.
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Makara Journal of Health Research
Makara Journal of Health Research MEDICINE, RESEARCH & EXPERIMENTAL-
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