Naproxen Induced Psoriasis: A Case Report

Copyright © 2019 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/ by/4.0) ABSTRACT Psoriasis is a chronic inflammatory skin disorder clinically characterized by erythematous, sharply demarcated papules and rounded plaques covered by silvery micaceous scale. There are several drugs that have been associated with the initiation, exacerbation, and aggravation of psoriasis. Understanding the pathophysiology can provide clues to treatment and management of druginduced and drug-aggravated psoriasis, which may be indistinguishable from idiopathic psoriasis. The clinical manifestations of drug-associated psoriasis can range from Plaque type psoriasis to severe Erythroderma, thus warranting astute and sustained clinical observation. Some factors known to trigger psoriasis include smoking, alcohol consumption, body mass index, trauma, infection, endocrine disorders, drugs. Drugs that appear to have a strong relationship to psoriasis are beta-blockers, lithium, synthetic antimalarials, NSAIDS and tetracyclines. Non steroidal anti inflammatory drugs(NSAIDS) are a class of medications used for treatment of pain and arthritides. It is important for clinicians to recognize NSAIDS as potential exacerbators of psoriasis. Exacerbation of psoriasis and arthritis may coincidently occur simultaneously with the use of NSAIDS.