基于纳米医学的核酸与抗癌纳米药物联合抗癌治疗:以透明质酸、海藻酸和透明质酸钠作为抗癌纳米药物和核酸的共价纳米药物递送系统选择性成像和治疗人类脑肿瘤

A. Heidari
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引用次数: 76

摘要

利用透明质酸、海藻酸和透明质酸钠(图1和2)作为同步辐射下的抗癌纳米药物和核酸递送,作为合成电子和光学活性聚合物的一种替代方法,已经被探索用于选择性成像和治疗人类脑肿瘤的共价纳米药物递送系统中的纳米药物与抗癌纳米药物联合抗癌治疗具有若干优点1-33。辣根过氧化物酶(HRP)以芳香质子供体为代价催化过氧化氢(H2O2)的分解。辣根过氧化物酶(HRP)是一种含铁卟啉型结构。在以往的工作中,我们合成了透明质酸,海藻酸和透明质酸钠,酶1-33。酶法聚合的结果与以往报道的透明质酸、海藻酸和透明质酸钠的化学和电化学聚合不同[1-33]。在这篇社论中,我们报道了苯胺和透明质酸、海藻酸和透明质酸钠与辣根过氧化物酶(HRP)在磺化聚苯乙烯(SPS)作为模板存在下的酶促共聚。
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Nanomedicine-Based Combination Anti-Cancer Therapy between Nucleic Acids and Anti-Cancer Nano Drugs in Covalent Nano Drugs Delivery Systems for Selective Imaging and Treatmentof Human Brain Tumors Using Hyaluronic Acid, Alguronic Acid and Sodium Hyaluronate as Anti-Cancer Nano Drugs and Nucleic Acid
Nanomedicine-based combination anti-cancer therapy between nucleic acids and anti-cancer Nano drugs in covalent Nano drugs delivery systems for selective imaging and treatment of human brain tumors using hyaluronic acid, alguronic acid and sodium hyaluronate (Figures 1 and 2) as anti-cancer Nano drugs and nucleic acids delivery under synchrotron radiation has been explored as an alternative approach to the synthesis of electronically and optically active polymers with several advantages1-33. Horseradish Peroxidase (HRP) catalyzes the decomposition of Hydrogen peroxide (H2O2) at the expense of aromatic proton donors. Horseradish Peroxidase (HRP) is a Fe containing porphyrin-type structure. In previous works, we synthesized hyaluronic acid, alguronic acid and sodium hyaluronate, enzymatically1-33. The results of enzymatic polymerization were different from chemical and electrochemical polymerization of hyaluronic acid, alguronic acid and sodium hyaluronate that reported previously1-33. In this editorial, we reported the enzymatic copolymerization of aniline and hyaluronic acid, alguronic acid and sodium hyaluronate with Horseradish Peroxidase (HRP) in the presence of Sulfonated Polystyrene (SPS) as a template.
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