关于药物开发的简述

L. Roche
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引用次数: 0

摘要

生物利用度指的是动态药物固定物或药物项目的动态部分被摄入并在药物活性部位打开的程度和速率。一般的生物利用度,就药物摄取的速度和程度而言,被视为临床结果的先见之明。1984年,美国食品和药物管理局(FDA)根据《药品价格竞争和专利期限恢复法案》,通过直接考虑生物利用度和生物等效性,批准常规药物项目依赖于药物同化中的正常生物等效性证明。
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Short Note on Drug Development
Bioavailability is alluded to as the degree and rate to which the dynamic medication fixing or dynamic moiety from the medication item is ingested and opens up at the site of medication activity. The general bioavailability as far as the rate and degree of medication ingestion is viewed as prescient of clinical results. In 1984, the United States Food and Drug Administration (FDA) was approved to endorse conventional medication items under the Drug Price Competition and Patent Term Restoration Act dependent on proof of normal bioequivalence in drug assimilation through the direct of bioavailability and bioequivalence considers.
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