儿童外伤性青光眼的分析

Y. Lyu, Yiran Wang
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The incidence of secondary glaucoma caused by closed ocular trauma (20.72%, 52/251) was higher than that of open ocular trauma (8.62%, 15/174), and the difference was statistically significant (χ2=11.323, P=0.001). The onset time of secondary glaucoma caused by closed ocular trauma was earlier than that of open ocular trauma. Hyphema (40.38%, 21/52) was the main cause of secondary glaucoma due to closed ocular trauma, and the mixed mechanism was the main cause of secondary glaucoma due to open ocular trauma (73.33%, 11/15). The two groups received conventional medicine first, and 22 cases (42.31%, 22/52) of closed ocular trauma group and 3 cases (20.00%, 3/15) in open ocular trauma group were converted to surgery because of lose control of IOP. The difference in surgery rate was not statistically significant between the two groups(χ2=2.477, P=0.116). At the last follow-up, the mean IOP of closed ocular trauma group was higher than that of open ocular trauma group (t=2.828, P=0.006). 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摘要

目的分析儿童外伤性青光眼的临床特点。方法回顾性研究。回顾性分析郑州大学附属第一医院2014年1月至2018年12月收治的425例1 ~ 14岁眼外伤儿童中67例继发性青光眼67只眼的资料。闭合性眼外伤致继发性青光眼52眼为闭合性眼外伤组,开放性眼外伤致继发性青光眼15眼为开放性眼外伤组。分析两组患者的临床特点、治疗方法及疗效。随访时间1个月~ 2年。结果儿童闭合性眼外伤251例,开放性眼外伤174例。闭合性眼外伤继发性青光眼发生率(20.72%,52/251)高于开放性眼外伤继发性青光眼发生率(8.62%,15/174),差异有统计学意义(χ2=11.323, P=0.001)。闭合性眼外伤继发性青光眼发病时间早于开放性眼外伤。前房积血是闭合性眼外伤继发性青光眼的主要原因(40.38%,21/52),混合性机制是开放性眼外伤继发性青光眼的主要原因(73.33%,11/15)。两组患者均先采用常规药物治疗,闭合性眼外伤组22例(42.31%,22/52),开放性眼外伤组3例(20.00%,3/15)因眼压失控转行手术治疗。两组手术率比较差异无统计学意义(χ2=2.477, P=0.116)。末次随访时,闭合性眼外伤组平均IOP高于开放性眼外伤组(t=2.828, P=0.006)。末次随访时两组患者BCVA差异无统计学意义(t=-1.244, P=0.218)。结论闭合性眼外伤继发性青光眼较开放性眼外伤更为常见。药物治疗仍是首选,但滤过手术是控制闭合性眼外伤继发性青光眼的有效方法。关键词:青光眼;外伤性;儿童;外伤,眼闭;外伤,眼睛,打开
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Analysis of traumatic glaucoma in children
Objective To analyze the clinical characteristics of traumatic glaucoma in children. Methods This is a retrospective study.The data of 67 eyes of 67 cases with secondary glaucoma in 425 children with ocular trauma, aged 1 to 14 years, from Jan. 2014 to Dec. 2018 in First Affiliated Hospital of Zhengzhou University were analysed retrospectively. There were 52 eyes of 52 cases with secondary glaucoma caused by closed ocular trauma in closed ocular trauma group, and 15 eyes of 15 cases with secondary glaucoma caused by open ocular trauma in open ocular trauma group. The clinical characteristics, treatment methods and efficacy of treatment of the two groups were analyzed. The follow-up time was 1 month- 2 years. Results There were 251 cases of closed ocular trauma and 174 cases of open ocular trauma in children. The incidence of secondary glaucoma caused by closed ocular trauma (20.72%, 52/251) was higher than that of open ocular trauma (8.62%, 15/174), and the difference was statistically significant (χ2=11.323, P=0.001). The onset time of secondary glaucoma caused by closed ocular trauma was earlier than that of open ocular trauma. Hyphema (40.38%, 21/52) was the main cause of secondary glaucoma due to closed ocular trauma, and the mixed mechanism was the main cause of secondary glaucoma due to open ocular trauma (73.33%, 11/15). The two groups received conventional medicine first, and 22 cases (42.31%, 22/52) of closed ocular trauma group and 3 cases (20.00%, 3/15) in open ocular trauma group were converted to surgery because of lose control of IOP. The difference in surgery rate was not statistically significant between the two groups(χ2=2.477, P=0.116). At the last follow-up, the mean IOP of closed ocular trauma group was higher than that of open ocular trauma group (t=2.828, P=0.006). There was no statistical significance in BCVA between the two groups at the last follow-up (t=-1.244, P=0.218). Conclusion Secondary glaucoma caused by closed ocular trauma is more common than open ocular trauma. Treatment with medicine is still the first choice, but filtering surgery is an effective way to control secondary glaucoma with closed ocular trauma. Key words: Glaucoma, traumatic, children; Trauma, ocular, closed; Trauma, ocular, open
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