时滞分数阶HIV模型解析性质的研究——以实例为例

M. Pitchaimani, A. Devi
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引用次数: 2

摘要

在这篇论文中,我们设计了一个分数阶延迟微分方程模型,用于HIV传播,并针对三个不同的感染阶段实施三种不同的治疗方法。我们研究了解的正性,分析了稳定性,然后进行了Hopf分岔分析。为了探索加速感染传播的参数,进行了不确定性和敏感性分析。进行了数值复核以证实我们的理论结果。我们提出的模型参数已经过校准,以适应来自阿富汗、澳大利亚、法国、意大利、荷兰和新西兰的年度数据。
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An Investigation on Analytical Properties of Delayed Fractional Order HIV Model: A Case Study
In this manuscript, we design a fractional order delay differential equation model for HIV transmission with the implementation of three distinct therapies for three different infectious stages. We investigate the positivity of solutions, analyze the stability properties, followed by Hopf bifurcation analysis. To probe the parameters that expedite the spread of infection, uncertainty and sensitivity analysis were performed. The numerical review was carried out to substantiate our theoretical results. Our proposed model parameters have been calibrated to fit yearly data from Afghanistan, Australia, France, Italy, Netherlands and New Zealand.
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来源期刊
Mathematical Biology and Bioinformatics
Mathematical Biology and Bioinformatics Mathematics-Applied Mathematics
CiteScore
1.10
自引率
0.00%
发文量
13
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