{"title":"时滞分数阶HIV模型解析性质的研究——以实例为例","authors":"M. Pitchaimani, A. Devi","doi":"10.17537/2021.16.57","DOIUrl":null,"url":null,"abstract":"\nIn this manuscript, we design a fractional order delay differential equation model for HIV transmission with the implementation of three distinct therapies for three different infectious stages. We investigate the positivity of solutions, analyze the stability properties, followed by Hopf bifurcation analysis. To probe the parameters that expedite the spread of infection, uncertainty and sensitivity analysis were performed. The numerical review was carried out to substantiate our theoretical results. Our proposed model parameters have been calibrated to fit yearly data from Afghanistan, Australia, France, Italy, Netherlands and New Zealand.\n","PeriodicalId":53525,"journal":{"name":"Mathematical Biology and Bioinformatics","volume":"1 1","pages":"57-85"},"PeriodicalIF":0.0000,"publicationDate":"2021-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"An Investigation on Analytical Properties of Delayed Fractional Order HIV Model: A Case Study\",\"authors\":\"M. Pitchaimani, A. Devi\",\"doi\":\"10.17537/2021.16.57\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\nIn this manuscript, we design a fractional order delay differential equation model for HIV transmission with the implementation of three distinct therapies for three different infectious stages. We investigate the positivity of solutions, analyze the stability properties, followed by Hopf bifurcation analysis. To probe the parameters that expedite the spread of infection, uncertainty and sensitivity analysis were performed. The numerical review was carried out to substantiate our theoretical results. Our proposed model parameters have been calibrated to fit yearly data from Afghanistan, Australia, France, Italy, Netherlands and New Zealand.\\n\",\"PeriodicalId\":53525,\"journal\":{\"name\":\"Mathematical Biology and Bioinformatics\",\"volume\":\"1 1\",\"pages\":\"57-85\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-05-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Mathematical Biology and Bioinformatics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17537/2021.16.57\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Mathematics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mathematical Biology and Bioinformatics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17537/2021.16.57","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Mathematics","Score":null,"Total":0}
An Investigation on Analytical Properties of Delayed Fractional Order HIV Model: A Case Study
In this manuscript, we design a fractional order delay differential equation model for HIV transmission with the implementation of three distinct therapies for three different infectious stages. We investigate the positivity of solutions, analyze the stability properties, followed by Hopf bifurcation analysis. To probe the parameters that expedite the spread of infection, uncertainty and sensitivity analysis were performed. The numerical review was carried out to substantiate our theoretical results. Our proposed model parameters have been calibrated to fit yearly data from Afghanistan, Australia, France, Italy, Netherlands and New Zealand.