联合MRI超分辨率和吉布斯伪影去除的无监督框架

Yikang Liu, Eric Z. Chen, Xiao Chen, Terrence Chen, Shanhui Sun
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摘要

由磁共振成像(MRI)产生的k空间数据只是底层信号的有限采样。因此,MRI图像经常遭受低空间分辨率和吉布斯响伪影。先前的研究分别解决了这两个问题,其中超分辨率方法倾向于增强吉布斯伪影,而吉布斯振铃去除方法倾向于模糊图像。在临床MRI中难以获得高分辨率的地面真实也是一个挑战。在本文中,我们提出了一个无监督学习框架,用于MRI超分辨率和Gibbs伪影去除,而不使用高分辨率的基础真值。此外,我们提出了正则化方法来提高模型在非分布MRI图像中的泛化性。我们用其他最先进的方法对8个具有不同对比和解剖结构的MRI数据集进行了评估。我们的方法不仅实现了最佳的SR性能,而且显著减少了吉布斯伪影。我们的方法还在不同的数据集上表现出良好的泛化性,这有利于临床应用,因为训练数据通常是稀缺和有偏见的。
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An Unsupervised Framework for Joint MRI Super Resolution and Gibbs Artifact Removal
The k-space data generated from magnetic resonance imaging (MRI) is only a finite sampling of underlying signals. Therefore, MRI images often suffer from low spatial resolution and Gibbs ringing artifacts. Previous studies tackled these two problems separately, where super resolution methods tend to enhance Gibbs artifacts, whereas Gibbs ringing removal methods tend to blur the images. It is also a challenge that high resolution ground truth is hard to obtain in clinical MRI. In this paper, we propose an unsupervised learning framework for both MRI super resolution and Gibbs artifacts removal without using high resolution ground truth. Furthermore, we propose regularization methods to improve the model's generalizability across out-of-distribution MRI images. We evaluated our proposed methods with other state-of-the-art methods on eight MRI datasets with various contrasts and anatomical structures. Our method not only achieves the best SR performance but also significantly reduces the Gibbs artifacts. Our method also demonstrates good generalizability across different datasets, which is beneficial to clinical applications where training data are usually scarce and biased.
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