西班牙成年人糖尿病与龋齿之间的关系:一项包括23,089名成年人的横断面研究

L. Jacob, J. Shin, I. Grabovac, J. Haro, A. Koyanagi, M. Tully, M. Trott, Jong Yeob Kim, S. Pardhan, Lee Smith, G. F. López Sánchez
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摘要

该研究的目的是调查糖尿病和龋齿之间的横断面关系,研究对象为23,089名居住在西班牙的成年人。分析了2017年西班牙国家健康调查的数据。糖尿病(自变量)和龋齿(因变量)通过自我报告问卷进行评估。在整个样本中,糖尿病和龋齿之间的关系通过调整性别、年龄、婚姻状况、教育程度、吸烟、饮酒、肥胖、高血压和高胆固醇血症等因素的logistic回归模型进行评估。总体人群龋齿患病率为20.6%,男性、青年(≤40岁)和中年人(41-65岁)的龋齿患病率分别高于女性和老年人(>65岁)。在调整控制变量后,总体人群中糖尿病和龋齿之间存在显著正相关(OR = 1.30, 95% CI = 1.15-1.46)。糖尿病与龋齿之间的关系在女性(OR = 1.45, 95% CI = 1.22-1.71)和≤40岁的成年人(OR = 1.80, 95% CI = 1.05-3.05)中尤为明显。总之,在这个西班牙成年人的大型代表性样本中,糖尿病与更高的龋齿患病率相关,女性和年轻人的风险最大。糖尿病患者和牙科医生应该意识到这些关联,并采取相应的行动。未来的研究应着眼于探讨糖尿病与龋病之间的关联的中介因素。
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Association between Diabetes and Dental Caries in Spanish Adults: A Cross-Sectional Study Including 23,089 Adults
The aim of the study was to investigate the cross-sectional association between diabetes and dental caries in a representative sample of 23,089 adults residing in Spain. Data from the Spanish National Health Survey 2017 were analysed. Diabetes (independent variable) and dental caries (dependent variable) were evaluated through a self-reported questionnaire. The association between diabetes and dental caries in the overall sample was assessed using logistic regression models adjusted for sex, age, marital status, education, smoking, alcohol consumption, obesity, hypertension, and hypercholesterolemia. The prevalence of dental caries was 20.6% in the overall population and was significantly higher in men and in young (≤40 years) and middle-aged adults (41–65 years) than in women and older adults (>65 years), respectively. After adjusting for control variables, there was a positive and significant association between diabetes and dental caries in the overall population (OR = 1.30, 95% CI = 1.15–1.46). The relationship between diabetes and dental caries was particularly strong in women (OR = 1.45, 95% CI = 1.22–1.71) and in adults aged ≤40 years (OR = 1.80, 95% CI = 1.05–3.05). In conclusion, in this large representative sample of Spanish adults, diabetes was associated with having a higher prevalence of dental caries, with females and younger adults at greatest risk. Patients with diabetes and dental practitioners should be aware of these associations and act accordingly. Future research should aim to investigate the mediating factors involved in the observed association between diabetes and dental caries.
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