香豆素脊乳头状纤维弹性瘤致脑栓塞1例

IF 0.1 Q4 NEUROSCIENCES Neurosonology and Cerebral Hemodynamics Pub Date : 2022-04-30 DOI:10.2301/neurosonology.35.9
R. Shirasawa, H. Takekawa, Shu Inami, S. Toyoda, H. Fukuda, K. Ohikata, S. Konno
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引用次数: 0

摘要

心脏乳头状纤维弹性瘤(CPF)通常起源于瓣膜,但很少形成于香豆素脊(CR),可引起脑栓塞。我们报告一位不寻常的79岁男性,在CR中出现CPF引起的脑栓塞,患者表现为右上肢麻痹,并被诊断为左卵圆体梗死。各项检查均未发现心房颤动和严重的脑动脉及颈动脉狭窄。虽然经胸超声心动图未显示异常,但经食管超声心动图(TEE)显示CR尖端有一个约11毫米的可移动的弦状结构。我们怀疑CR上有血栓,并给予抗凝治疗,但该结构并未消失。因此,患者被诊断为心脏肿瘤,并接受肿瘤切除和左心房附件手术关闭。经组织病理证实为CPF。继续华法林治疗,术后4个月无肿瘤复发或脑栓塞。隐源性脑卒中应考虑CPF,特别是不明来源脑栓塞的栓塞性脑卒中。
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A case of cerebral embolism due to papillary fibroelastoma in the coumadin ridge
Cardiac papillary fibroelastoma (CPF) is often of valvular origin, but rarely forms in coumadin ridge (CR) and may cause cerebral embolism. We present an unusual 79-year-old man with cerebral embolism caused by CPF in CR. The patient presented with right upper limb paresis and was diagnosed with left centrum ovale infarction. Atrial fibrillation and severe stenosis of the cerebral and carotid artery were not found in various examinations. Although transthoracic echocardiography showed no abnormalities, transesophageal echocardiography (TEE) revealed a mobile string-like structure measuring approximately 11 mm at the tip of the CR. We suspected a thrombus attached to the CR, and anticoagulation therapy was administered, however the structure did not dis-appear. Therefore, the patient was diagnosed as cardiac tumor and underwent tumor excision and surgical clo-sure of the left atrial appendage. The tumor was confirmed to be CPF on histopathology. Warfarin therapy was continued, and there was no recurrence of tumor or cerebral embolism at 4 months after surgery. CPF should be considered in cryptogenic stroke, especially in embolic stroke of undetermined sources cerebral embolism.
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