Fabrication of Interdigitated Microelectrodes in Microfluidic Channel

Biosensors have become widespread in various domains in biomedical and life science applications. The bioreceptor as the second main component along with transducer to meet the architecture of the biosensors. The bioreceptor’s configuration should follow up the development of biosensors to catch up the research needs in simple, fast, and low cost techniques. Micro/Nanotechnology provides high transducers performance, where the development of bioreceptor has other tasks to be considered. The major tasks that should be taking into account to achieve the bioreceptor development are but not limited to selectivity, sensitivity, design and packaging. Interdigitated Microelectrode Array (IDMA) that lies on the surface of microfluidic channel (MFC) plays an important role in biosensors development. An easy, cheap, rapid process to fabricate IDMA using softphotolithography technique will be unfolded. The beneficial of the new bioreceptor is applicable in many biomedical and biological applications such as biomarker detection, cancer clinical testing, detection of infectious microorganisms and viruses. Moreover, it is strongly contributing the development of biosensors and work as Aptasensor. The electrochemical impedance spectroscopy (EIS) is the approach that will imply to detect the variation on the surface of MFC as a sensing surface layer. Keywords-Biosensors, Bioreceptor, Aptasensor, MLoC, IDMA, DNA, EIS.