Angel Mangiwa, Mirna Maulidah, Tipalmaton R Patulen, Dhea K Kende, I. Ismail, Desy A Lestari, Maulita Indrisari, L. Muslimin
{"title":"三叶草浸提液与煎提液抗氧化活性的比较研究多明)","authors":"Angel Mangiwa, Mirna Maulidah, Tipalmaton R Patulen, Dhea K Kende, I. Ismail, Desy A Lestari, Maulita Indrisari, L. Muslimin","doi":"10.36490/journal-jps.com.v6i3.55","DOIUrl":null,"url":null,"abstract":"The number of patients with neurodegenerative disorders increased, especially in the productive age. The neurodegenerative disorder can be prevented by synthetic and natural antioxidants such as from plants. The herb of galling, Cayratia trifolia (L.) Domin), has long been traditionally used to prevent degenerative diseases by drinking decoction. The current study aimed to compare the antioxidant capability between infusion and decoction of galling against DPPH. The herbs were extracted with two methods, namely infusion, and decoction. This study used 7 different serial concentrations ranging 7.81 till 500 µg/mL, while the optical density was recorded at 515 nm using a spectrophotometer. The results demostrated that both infusion and decoction have antioxidant activity against DPPH with IC50 values of 87.55±1.01 (strong category) and 65.38±2.26 µg/mL (strong category), respectively. There was a statistically significant (p<0.05) between the IC50 values of infusion and decoction. In conclusion, galling is efficacious as an antioxidant source for preventing and treating degenerative diseases.","PeriodicalId":50090,"journal":{"name":"Journal of Pharmacy and Pharmaceutical Sciences","volume":null,"pages":null},"PeriodicalIF":2.9000,"publicationDate":"2023-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Comparative Study on Antioxidant Activity of Infusion and Decoction of (Cayratia trifolia (L.) Domin)\",\"authors\":\"Angel Mangiwa, Mirna Maulidah, Tipalmaton R Patulen, Dhea K Kende, I. Ismail, Desy A Lestari, Maulita Indrisari, L. Muslimin\",\"doi\":\"10.36490/journal-jps.com.v6i3.55\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The number of patients with neurodegenerative disorders increased, especially in the productive age. The neurodegenerative disorder can be prevented by synthetic and natural antioxidants such as from plants. The herb of galling, Cayratia trifolia (L.) Domin), has long been traditionally used to prevent degenerative diseases by drinking decoction. The current study aimed to compare the antioxidant capability between infusion and decoction of galling against DPPH. The herbs were extracted with two methods, namely infusion, and decoction. This study used 7 different serial concentrations ranging 7.81 till 500 µg/mL, while the optical density was recorded at 515 nm using a spectrophotometer. The results demostrated that both infusion and decoction have antioxidant activity against DPPH with IC50 values of 87.55±1.01 (strong category) and 65.38±2.26 µg/mL (strong category), respectively. There was a statistically significant (p<0.05) between the IC50 values of infusion and decoction. In conclusion, galling is efficacious as an antioxidant source for preventing and treating degenerative diseases.\",\"PeriodicalId\":50090,\"journal\":{\"name\":\"Journal of Pharmacy and Pharmaceutical Sciences\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2023-07-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pharmacy and Pharmaceutical Sciences\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.36490/journal-jps.com.v6i3.55\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pharmacy and Pharmaceutical Sciences","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.36490/journal-jps.com.v6i3.55","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
A Comparative Study on Antioxidant Activity of Infusion and Decoction of (Cayratia trifolia (L.) Domin)
The number of patients with neurodegenerative disorders increased, especially in the productive age. The neurodegenerative disorder can be prevented by synthetic and natural antioxidants such as from plants. The herb of galling, Cayratia trifolia (L.) Domin), has long been traditionally used to prevent degenerative diseases by drinking decoction. The current study aimed to compare the antioxidant capability between infusion and decoction of galling against DPPH. The herbs were extracted with two methods, namely infusion, and decoction. This study used 7 different serial concentrations ranging 7.81 till 500 µg/mL, while the optical density was recorded at 515 nm using a spectrophotometer. The results demostrated that both infusion and decoction have antioxidant activity against DPPH with IC50 values of 87.55±1.01 (strong category) and 65.38±2.26 µg/mL (strong category), respectively. There was a statistically significant (p<0.05) between the IC50 values of infusion and decoction. In conclusion, galling is efficacious as an antioxidant source for preventing and treating degenerative diseases.
期刊介绍:
The Journal of Pharmacy and Pharmaceutical Sciences (JPPS) is the official journal of the Canadian Society for Pharmaceutical Sciences. JPPS is a broad-spectrum, peer-reviewed, international pharmaceutical journal circulated electronically via the World Wide Web. Subscription to JPPS is free of charge. Articles will appear individually as soon as they are accepted and are ready for circulation.