68岁女性，肺结节内含有341个循环异常细胞

Clinical eHealth Pub Date : 2022-12-01 DOI:10.1016/j.ceh.2022.11.002

Lu Wang , Dawei Yang , Lin Tong , Yuanlin Song , Chunxue Bai

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引用次数: 0

摘要

背景:正确的诊断和治疗是提高肺癌患者生存和预后的关键。液体活检和人工智能(AI)可以帮助诊断早期肺癌。我们报告一位68岁女性，有肺结节家族史，无吸烟史，体检时发现肺部多发结节。通过人工智能评价和341个循环异常细胞(CACs)诊断恶性肺结节。手术切除证实肺腺癌的诊断，术后随访1个月cac降至151，术后6个月cac降至54。结论cacs有助于提高早期肺癌AI诊断的准确性和肺癌患者随访时的预后。

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A 68-year-old female with pulmonary nodules harboring 341 circulating abnormal cells

Background

Early diagnosis and treatment are key to improving survival and prognosis of patients with lung cancer. Liquid biopsy and artificial intelligence (AI) can help diagnose early lung cancer.

Case presentation

We present a 68-year-old female with a family history of pulmonary nodules without smoking history who found multiple nodules in the lungs on physical examination. Malignant lung nodules were diagnosed based on AI evaluation and 341 circulating abnormal cells (CACs). Surgical resection confirmed the diagnosis of pulmonary adenocarcinoma and the CACs decreased to 151 at postoperative follow-up in one month and to 54 six months after surgery.