E. Dias, J. Caldeira, Margarida Pimenta Queiroz Valério, Ana Maria da Fonseca Arrobas Correia de Matos
{"title":"吸入皮质类固醇治疗哮喘和骨质疏松症","authors":"E. Dias, J. Caldeira, Margarida Pimenta Queiroz Valério, Ana Maria da Fonseca Arrobas Correia de Matos","doi":"10.15406/jlprr.2020.07.00231","DOIUrl":null,"url":null,"abstract":"followed fluticasone propionate (n=2, 28.6%). One is on high dose budesonide (>800 µg/day), 1 medium dose budesonide (> 400-800µg/day), 3 low dose budesonide (200-400 µg/ day), 1 high dose fluticasone (>500µg/day) and 1 patient low dose fluticasone (100-250µg/day). Inhaled corticosteroids (ICS) are widely used in the treatment of asthma but their safety on bone density is controversial. 1 Bone mineral density (BMD) is assessed by DEXA - dual energy radiologic absorptiometry (osteodensitometry) - performed at the proximal femur and lumbar spine levels. The absolute BMD values and the T-score (femoral neck, total hip and lumbar spine) should be taken into account in postmenopausal women and in men over 50 years of age (T-score≥-1:normal; -2.5<T-score<-1:osteopenia; T-score≤-2.5:osteoporosis). In premenopausal","PeriodicalId":91750,"journal":{"name":"Journal of lung, pulmonary & respiratory research","volume":"27 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Inhaled corticosteroid therapy in Asthma and Osteoporosis\",\"authors\":\"E. Dias, J. Caldeira, Margarida Pimenta Queiroz Valério, Ana Maria da Fonseca Arrobas Correia de Matos\",\"doi\":\"10.15406/jlprr.2020.07.00231\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"followed fluticasone propionate (n=2, 28.6%). One is on high dose budesonide (>800 µg/day), 1 medium dose budesonide (> 400-800µg/day), 3 low dose budesonide (200-400 µg/ day), 1 high dose fluticasone (>500µg/day) and 1 patient low dose fluticasone (100-250µg/day). Inhaled corticosteroids (ICS) are widely used in the treatment of asthma but their safety on bone density is controversial. 1 Bone mineral density (BMD) is assessed by DEXA - dual energy radiologic absorptiometry (osteodensitometry) - performed at the proximal femur and lumbar spine levels. The absolute BMD values and the T-score (femoral neck, total hip and lumbar spine) should be taken into account in postmenopausal women and in men over 50 years of age (T-score≥-1:normal; -2.5<T-score<-1:osteopenia; T-score≤-2.5:osteoporosis). In premenopausal\",\"PeriodicalId\":91750,\"journal\":{\"name\":\"Journal of lung, pulmonary & respiratory research\",\"volume\":\"27 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-09-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of lung, pulmonary & respiratory research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15406/jlprr.2020.07.00231\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of lung, pulmonary & respiratory research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15406/jlprr.2020.07.00231","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Inhaled corticosteroid therapy in Asthma and Osteoporosis
followed fluticasone propionate (n=2, 28.6%). One is on high dose budesonide (>800 µg/day), 1 medium dose budesonide (> 400-800µg/day), 3 low dose budesonide (200-400 µg/ day), 1 high dose fluticasone (>500µg/day) and 1 patient low dose fluticasone (100-250µg/day). Inhaled corticosteroids (ICS) are widely used in the treatment of asthma but their safety on bone density is controversial. 1 Bone mineral density (BMD) is assessed by DEXA - dual energy radiologic absorptiometry (osteodensitometry) - performed at the proximal femur and lumbar spine levels. The absolute BMD values and the T-score (femoral neck, total hip and lumbar spine) should be taken into account in postmenopausal women and in men over 50 years of age (T-score≥-1:normal; -2.5