手术夹持颅内动脉瘤破裂:印度西部一家三级中心的经验

IF 0.3 Q4 SURGERY Indian Journal of Neurosurgery Pub Date : 2022-04-26 DOI:10.1055/s-0042-1743400
Vijay Kumar, M. Agrawal, Vinod Sharma, D. Purohit
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引用次数: 0

摘要

背景手术夹闭一直是治疗颅内动脉瘤的金标准方法。在机构层面对手术夹持的结果进行研究对于确定可改变的因素和进一步改善结果是重要的。在资源有限、患者因无知和缺乏教育而迟到的地区,这一点尤为重要。本研究回顾了我院显微外科手术治疗颅内动脉瘤破裂的经验。方法回顾性分析2014年1月至2020年2月行颅内动脉瘤破裂手术夹持的患者。对患者的医疗记录进行了人口统计数据、临床表现、放射学调查、手术和神经学结果的审查。采用改良Rankin量表(mRS)测量出院时和随访时的预后。结果289例患者出院时预后良好(mr50 - 2) 194例(67.13%),出院时预后不良(mr3 - 6) 95例(32.87%),住院期间死亡50例(17.30%)。289例患者中,208例(71.97%)患者入院时间超过3天。影响预后的重要因素是由格拉斯哥昏迷量表(GCS)评分、世界神经外科学会联合会(WFNS)分级或Hunt and Hess分级、从蛛网膜下腔出血开始到入院的时间间隔以及从入院到手术的时间间隔确定的神经状态。结论本研究在机构和社区层面确定了改善动脉瘤破裂患者预后的因素。在我们的研究中,从发作到入院和入院手术的时间是重要的可改变因素。
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Surgical Clipping of Ruptured Intracranial Aneurysm: Experience of a Tertiary Centre in Western India
Background Surgical clipping has been a gold standard procedure for management of intracranial aneurysms. Outcome studies of surgical clipping at institutional level are important to identify modifiable factors and further improve the results. These are even more important in areas where resources are limited, and patient presents late due to ignorance and lack of education. This study is a review of our institutional experience in microsurgical clipping of ruptured intracranial aneurysms. Methods A retrospective study of patients who underwent surgical clipping for ruptured intracranial aneurysms from January 2014 to February 2020. The medical records of patients were reviewed for demographic data, clinical presentation, radiological investigations, surgery performed and neurological outcome. Outcome at discharge and outcome at follow-up were measured by modified Rankin scale (mRS). Results In this study of 289 patients, 194 patients (67.13%) had good outcome at discharge (mRS0–2), while 95 patients (32.87%) had poor outcome at discharge (mRS 3–6) and 50 patients (17.30%) expired during hospital stay. Out of 289 patients, 208 patients (71.97%) were admitted after more than 3 days of ictus. Significant factors affecting outcome were neurological status determined by Glasgow coma scale (GCS) score, World Federation of Neurosurgical Societies (WFNS) grade or Hunt and Hess Grade, time interval from onset of subarachnoid hemorrhage to admission, and time interval from admission to surgery. Conclusion The present study identifies factors for improving outcome in patients of ruptured aneurysm at institutional and community level. Time from ictus to admission and admission to surgery are important modifiable factors in our study.
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12 weeks
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