阴茎癌腹股沟淋巴结切除术的未来:腹腔镜还是机器人?

L. Favorito
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引用次数: 3

摘要

2019年3 - 4月出版的《国际膀胱杂志》在不同领域发表了许多有趣的原创论文:前列腺癌、肾结石、肾细胞癌、膀胱癌、尿道狭窄、创伤、前列腺活检、肾移植、神经源性膀胱和阴茎癌。这些论文来自许多不同的国家,如巴西、美国、土耳其、中国、意大利、伊朗、阿根廷、西班牙、韩国和英国,和往常一样,编辑的评论突出了一些论文。我们决定评论一个非常有趣的话题:阴茎癌腹股沟淋巴结的治疗。来自巴西的Meneses医生和他的同事在325页上做了一个有趣的研究,关于视频内窥镜下治疗阴茎癌的腹沟淋巴结切除术。作者描述了使用这种方法的初步经验,并分析了11例阴茎癌(T2或T3期)的术后并发症。观察出血、引流时间、蜂窝织炎、淋巴囊肿、皮肤坏死、微皮坏死及住院时间。本文结果显示,无一例患者出现术中并发症、出血> 50ml或转化。总并发症发生率为33.2%(27.2%为淋巴并发症)。无患者出现皮肤坏死。结论:视频内镜下治疗阴茎癌腹股沟淋巴结切除术是一种安全、简便、并发症发生率低的技术。阴茎恶性肿瘤是一种罕见的疾病,多见于社会经济水平较低的地区,约占男性恶性肿瘤的2%,其中鳞状细胞癌(SCC)是最常见的类型(1,2)。考虑到肿瘤的播散优先通过淋巴(最初为腹股沟浅淋巴结,后来为腹股沟深淋巴结和盆腔淋巴结),腹股沟淋巴结转移的存在是影响这些患者生存的主要变量(3)。因此,双侧腹股沟淋巴结切除术是唯一能够早期识别和治疗腹股沟微转移的手术,尽管其预防适应症在文献中存在争议(4-6)。以下是淋巴结切除术的主要适应症:肿瘤> 2cm,肿瘤级别高(组织病理学分级为II级或III级),局部分期晚期(T2-T4),淋巴血管镜下浸润,抗生素治疗后可触及腹股沟淋巴结,随访中出现无远处病变证据且临床评价不理想的腹股沟淋巴结(肥胖,腹股沟手术)(4)。腹股沟淋巴结切除术是治疗的重要阶段。然而,应该注意的是,大约50%的患者提交了open Vol. 45 (2): 208-209, March - April, 2019
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The future of inguinal Lymphadenecotmy in penile cancer: laparoscopic or robotic?
The March-April 2019 issue of the International Braz J Urol presents original contributions with a lot of interesting papers in different fields: Prostate Cancer, Renal stones, Renal Cell Carcinoma, Bladder Cancer, Uretrhal Strictures, Trauma, Prostate Biopsy, Kidney Transplant, neurogenic Bladder and Penile Cancer. The papers come from many different countries such as Brazil, USA, Turkey, China, Italy, Iran, Argentina, Spain, South Korea, and United Kingdon, and as usual the editor’s comment highlights some papers. We decided to comment the paper about a very interesting topic: The treatment of the inguinal lymph nodes in penile cancer. Doctor Meneses and collegues from Brazil performed on page 325 an interesting study about the Video Endoscopic management of inguinal lympadenectomy in penile cancer. The authors described the initial experience with this method and analyzed the post-surgical complications in 11 patients with penile cancer (stages T2 or T3). They observed the bleeding, drainage time, cellulitis, lymphocele, cutaneous necrosis, miocutaneous necrosis and hospitalization time. The results of the paper shows that no patient showed intrasurgical complications, bleeding > 50 mL or conversion. The global complication rate was 33.2% (27.2% were lymphatic). No patient showed cutaneous necrosis. The authors concluded that video endoscopic management of inguinal lympadenectomy in penile cancer is a safe and easy technique with lower incidence of complications. Malignant neoplasm of the penis is a rare disease, being more common in regions with low socioeconomic levels, accounting for approximately 2% of malignancies in man, with squamous cell carcinoma (SCC) being the most common type (1, 2). Considering that tumor dissemination is preferentially done lymphatic (initially for superficial inguinal lymph nodes and later for deep inguinal and pelvic lymph nodes), the presence of metastases in the inguinal lymph nodes is the main variable capable of affecting the survival in these patients (3). In this way, bilateral inguinal lymphadenectomy represents the only procedure capable of identifying and treating inguinal micrometastases early, although its prophylactic indication is controversial in the literature (4-6). The following are the main indications of lymphadenectomy: tumors > 2 cm, high-grade tumors (histopathological grade II or III), advanced local staging (T2-T4), lymphovascular microscopic invasion, palpable inguinal lymph nodes after antibiotic therapy, palpable inguinal lymph nodes that appeared in the follow-up without evidence of distant disease and unsatisfactory clinical evaluation (obese, inguinal surgery) (4). Inguinal lymphadenectomy represents an important stage of treatment. However, it should be noted that about 50% of patients submitted to open Vol. 45 (2): 208-209, March April, 2019
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