韩国2019年5628例冠状病毒病患者的流行病学和临床特征:一项全国性多中心研究

Seung Won Lee, S. Moon, D. Yon
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引用次数: 3

摘要

目的:韩国实验室确诊的冠状病毒病2019 (COVID-19)患者的流行病学、临床特征和结局数据有限。我们的目的是利用韩国全国多中心数据库描述COVID-19患者的流行病学和临床特征以及结果。方法:在这项全国性的多中心研究中,我们纳入了2020年2月1日至4月30日在韩国确诊的所有COVID-19患者。研究对象分为3个年龄组:10岁以下(儿童)、10 ~ 20岁(青少年)和20岁及以上(成人)。采用实时逆转录-聚合酶链反应实验室检测确诊病例,分析流行病学和临床特征及转归。专利被跟踪到2020年4月30日。结果:5628例新冠肺炎患者中,男性2320例(41.2%),女性3308例(58.8%),其中儿童66例(1.2%),青少年206例(3.7%),成人5356例(95.2%)。常见合并症为高血压(1201例,21.3%)、糖尿病(691例,12.3%)、肺心病(224例,4.0%)、慢性心脏病(179例,3.2%)、癌症(145例,2.6%)、哮喘(128例,2.3%)。常见症状为咳嗽2341例(41.6%)、咳痰1619例(28.8%)、发热1305例(23.2%)、头痛967例(17.2%)、肌痛926例(16.5%)、舌痛881例(15.7%)。确诊为中重度165例(2.1%),确诊为重度118例(2.1%)。结论:我们的描述性研究提供了韩国实验室确诊的COVID-19患者的流行病学、临床特征和结局。(过敏哮喘呼吸疾病2021;9:36 -140)
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Epidemiological and clinical characteristics of 5,628 patients with coronavirus disease 2019 in South Korea: A nationwide multicenter study
Purpose: There are limited data on the epidemiological and clinical characteristics and outcomes in Korean patients with laboratory-confirmed coronavirus disease 2019 (COVID-19). We aimed to describe the epidemiological and clinical characteristics and outcomes of patients with COVID-19 using the Korean nationwide multicenter database. Methods: In this nationwide multicenter study, we included all confirmed patients of COVID-19 in South Korea from February 1 to April 30, 2020. Subjects were classified into 3 age groups: those at younger than 10 years (children), 10 to 20 years (adolescents), and 20 years or more (adults). Cases were confirmed by laboratory testing using real-time reverse transcriptase-polymerase chain reaction assay and analyzed for epidemiological and clinical features and outcomes. Patents were followed up until April 30, 2020. Results: Of 5,628 patients with COVID-19 (2,320 males [41.2%] and 3,308 females [58.8%]), there were 66 children (1.2%), 206 adolescents (3.7%), and 5,356 adults (95.2%). The common comorbidities were hypertension (1,201, 21.3%), diabetes (691, 12.3%), dementia (224, 4.0%), chronic heart disease (179, 3.2%), cancer (145, 2.6%), and asthma (128, 2.3%). The common presenting symptoms were cough (2,341, 41.6%), sputum (1,619, 28.8%), fever (1,305, 23.2%), headache (967, 17.2%), myalgia (926, 16.5%), and pharyngodynia (881, 15.7%). One hundred sixty-five patients (2.1%) were confirmed as having moderate or severe COVID-19 and 118 (2.1%) as having severe COVID-19. Conclusion: Our descriptive study provides the epidemiological and clinical characteristics and outcomes of patients with laboratory-confirmed COVID-19 in South Korea. (Allergy Asthma Respir Dis 2021;9:136-140)
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