30-55岁表面健康女性动脉粥样硬化指数和脂质比率的评估

Pub Date : 2021-08-19 DOI:10.5603/AH.A2021.0020
R. M. Gol, M. Rafraf, M. Jafarabadi
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引用次数: 1

摘要

背景:心血管疾病(CVD)是世界范围内死亡的主要原因,动脉粥样硬化性血脂异常是CVD的一个确定的危险因素。本横断面研究旨在评估2017年4 - 5月居住在伊朗大不里士的妇女的动脉粥样硬化指数和脂质比率,包括动脉粥样硬化系数(AC)、血浆动脉粥样硬化指数(AIP)、胆碱指数(CI)、castelli风险指数-1 (CRI-1)、CRI-2和非hdl - c。材料和方法:对伊朗大不里士150名30-55岁妇女的人体测量、空腹血脂和血压进行评估。用建立的公式计算动脉粥样硬化指数。结果:AIP、AC、CI、CRI-1、CRI-2、非hdl - c高患病率分别为64.5%、36.2%、20.4%、77%、7.2%、44.7%。多重校正分位数回归分析发现,CI比与舒张压(DBP) (B = 3.76, P = 0.035)、CRI-2比与DBP (B = 0.005, P = 0.042)与年龄(B = 0.005, P = 0.031)存在显著相关。结论:这项研究表明,根据动脉粥样硬化指数,大多数被研究的女性患心血管疾病的风险很高。需要进一步的公共卫生努力,以提高妇女和保健提供者对预防和控制心血管疾病风险的认识。
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Assessment of atherogenic indices and lipid ratios in the apparently healthy women aged 30–55 years
Background: Cardiovascular disease (CVD) is the main cause of death worldwide and atherogenic dyslipidemia is an established risk factor for CVD. This cross-sectional study aimed to assess the atherogenic indices and lipid ratios including atherogenic coefficient (AC), atherogenic index of plasma (AIP), cholindex (CI), castelli risk index-1 (CRI-1), CRI-2, and non-HDL-C in women living in the Tabriz, Iran during April – May 2017. Material and Methods: Anthropometric measurements, fasting serum lipids, and blood pressure of 150 women aged 30-55 years in Tabriz, Iran was evaluated. The atherogenic indices were calculated by the established formulas. Results: The prevalence of high AIP, AC, CI, CRI-1, CRI-2 and non-HDL-C ratios were 64.5%, 36.2%, 20.4%, 77%, 7.2% and 44.7%, respectively. In the multiple-adjusted quantile regression analysis, significant relationships were found between CI ratio and diastolic blood pressure (DBP) (B = 3.76, P = 0.035) and between CRI-2 ratio with DBP (B = 0.005, P = 0.042) and age (B = 0.005, P = 0.031). Conclusions: This study indicated that the majority of studied women had a high risk of CVD based on atherogenic indices. Further public health efforts are required to enhance awareness of women and healthcare providers about preventing and controlling CVD risk.
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