{"title":"大微血管成像鉴别甲状腺良恶性结节的准确诊断:一项荟萃分析","authors":"Y. Zhou, C. Wang","doi":"10.52547/ijrr.20.2.2","DOIUrl":null,"url":null,"abstract":"Background : Meta-analysis experiments can be used to judge the hypothesis of SMI benign and malignant thyroid nodules. Material and Methods : We explored Cochrane Library, PubMed, Google Scholar, CBM and Web of Science, databases according to the required content, and used a number of analysis equipment to analyze, and through the conclusions drawn to determine the sensitivity (Sen) and specificity (Spe), the probability ratio of pragmatic and dismissive (LR + / LR-), diagnostic factor (DOR) and receiver performance typical curve (SROC) are calculated for summary statistics. Results : The meta-analysis included nine studies that met the participation criteria. An aggregation of 636 malignant thyroid legumes and 732 benign thyroid nodules were evaluated. The comprehensive Sen was 0.79 (95% confidence interval (CI) = 0.76-0.82), and the comprehensive Spe was 0.89 (95% CI = 0.85-0.92). The comprehensive LR + was 7.04 (95% CI = 5.26-9.43), and the comprehensive negative LR- was 0.23 (95% CI = 0.20-0.27). The comprehensive DOR of thyroid nodules diagnosed by SMI was 30.33 (95% confidence interval = 20.73–44.38). The range beneath the SROC curve was 0.82 (95% confidence interval = 0.79 to 0.86). We established no proof of reporting bias (t = 0.91, P = 0.39). Conclusion : In a related meta-analysis, the study found that SMI has a very high prognosis accuracy in distinguishing malignant and benign thyroid nodules.","PeriodicalId":48815,"journal":{"name":"International Journal of Radiation Research","volume":"17 1","pages":""},"PeriodicalIF":0.4000,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"The accurate diagnosis of grand microvascular imaging in differentiating benign and malignant thyroid nodules: A meta-analysis\",\"authors\":\"Y. Zhou, C. Wang\",\"doi\":\"10.52547/ijrr.20.2.2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background : Meta-analysis experiments can be used to judge the hypothesis of SMI benign and malignant thyroid nodules. Material and Methods : We explored Cochrane Library, PubMed, Google Scholar, CBM and Web of Science, databases according to the required content, and used a number of analysis equipment to analyze, and through the conclusions drawn to determine the sensitivity (Sen) and specificity (Spe), the probability ratio of pragmatic and dismissive (LR + / LR-), diagnostic factor (DOR) and receiver performance typical curve (SROC) are calculated for summary statistics. Results : The meta-analysis included nine studies that met the participation criteria. An aggregation of 636 malignant thyroid legumes and 732 benign thyroid nodules were evaluated. The comprehensive Sen was 0.79 (95% confidence interval (CI) = 0.76-0.82), and the comprehensive Spe was 0.89 (95% CI = 0.85-0.92). The comprehensive LR + was 7.04 (95% CI = 5.26-9.43), and the comprehensive negative LR- was 0.23 (95% CI = 0.20-0.27). The comprehensive DOR of thyroid nodules diagnosed by SMI was 30.33 (95% confidence interval = 20.73–44.38). The range beneath the SROC curve was 0.82 (95% confidence interval = 0.79 to 0.86). We established no proof of reporting bias (t = 0.91, P = 0.39). Conclusion : In a related meta-analysis, the study found that SMI has a very high prognosis accuracy in distinguishing malignant and benign thyroid nodules.\",\"PeriodicalId\":48815,\"journal\":{\"name\":\"International Journal of Radiation Research\",\"volume\":\"17 1\",\"pages\":\"\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2022-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Radiation Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.52547/ijrr.20.2.2\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Radiation Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.52547/ijrr.20.2.2","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 1
摘要
背景:meta分析实验可用于判断SMI患者甲状腺结节良恶性假说。材料与方法:我们根据需要的内容对Cochrane Library、PubMed、Google Scholar、CBM和Web of Science等数据库进行了检索,并使用多种分析设备进行分析,通过得出的结论确定敏感性(Sen)和特异性(Spe),计算出语用与不屑一顾的概率比(LR + / LR-)、诊断因子(DOR)和接受者表现典型曲线(SROC)进行汇总统计。结果:荟萃分析包括9项符合参与标准的研究。恶性甲状腺结节636例,良性甲状腺结节732例。综合Sen为0.79(95%可信区间(CI) = 0.76 ~ 0.82),综合Spe为0.89 (95% CI = 0.85 ~ 0.92)。综合LR +为7.04 (95% CI = 5.26 ~ 9.43),综合LR-为0.23 (95% CI = 0.20 ~ 0.27)。SMI诊断甲状腺结节的综合DOR为30.33(95%可信区间= 20.73 ~ 44.38)。SROC曲线下极差为0.82(95%可信区间= 0.79 ~ 0.86)。我们没有建立报告偏倚的证据(t = 0.91, P = 0.39)。结论:在一项相关的meta分析中,研究发现SMI在鉴别甲状腺结节良恶性方面具有非常高的预后准确性。
The accurate diagnosis of grand microvascular imaging in differentiating benign and malignant thyroid nodules: A meta-analysis
Background : Meta-analysis experiments can be used to judge the hypothesis of SMI benign and malignant thyroid nodules. Material and Methods : We explored Cochrane Library, PubMed, Google Scholar, CBM and Web of Science, databases according to the required content, and used a number of analysis equipment to analyze, and through the conclusions drawn to determine the sensitivity (Sen) and specificity (Spe), the probability ratio of pragmatic and dismissive (LR + / LR-), diagnostic factor (DOR) and receiver performance typical curve (SROC) are calculated for summary statistics. Results : The meta-analysis included nine studies that met the participation criteria. An aggregation of 636 malignant thyroid legumes and 732 benign thyroid nodules were evaluated. The comprehensive Sen was 0.79 (95% confidence interval (CI) = 0.76-0.82), and the comprehensive Spe was 0.89 (95% CI = 0.85-0.92). The comprehensive LR + was 7.04 (95% CI = 5.26-9.43), and the comprehensive negative LR- was 0.23 (95% CI = 0.20-0.27). The comprehensive DOR of thyroid nodules diagnosed by SMI was 30.33 (95% confidence interval = 20.73–44.38). The range beneath the SROC curve was 0.82 (95% confidence interval = 0.79 to 0.86). We established no proof of reporting bias (t = 0.91, P = 0.39). Conclusion : In a related meta-analysis, the study found that SMI has a very high prognosis accuracy in distinguishing malignant and benign thyroid nodules.
期刊介绍:
International Journal of Radiation Research (IJRR) publishes original scientific research and clinical investigations related to radiation oncology, radiation biology, and Medical and health physics. The clinical studies submitted for publication include experimental studies of combined modality treatment, especially chemoradiotherapy approaches, and relevant innovations in hyperthermia, brachytherapy, high LET irradiation, nuclear medicine, dosimetry, tumor imaging, radiation treatment planning, radiosensitizers, and radioprotectors. All manuscripts must pass stringent peer-review and only papers that are rated of high scientific quality are accepted.