脑深部电刺激治疗特发性震颤

B. Bluett
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引用次数: 3

摘要

特发性震颤(ET)是最常见的运动障碍之一,可导致标准药物难以治疗的致残症状。1997年,美国食品和药物管理局批准对丘脑腹侧中间核进行深部脑刺激(DBS)治疗ET。DBS通常可以减少或消除治疗ET的药物需求。正确的患者选择和DBS编程的专业知识对于确保最佳结果至关重要。DBS的最新进展包括定向电流控制和多源独立恒流,以使每个电极具有自己的电源。本章讨论了脑起搏术治疗ET的正确患者选择、程序设计指南和临床要点。
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Deep Brain Stimulation for Essential Tremor
Essential tremor (ET) is one of the most common movement disorders and can result in disabling symptoms that are refractory to standard medications. In 1997, the US Food and Drug Administration approved deep brain stimulation (DBS) of the ventral intermedius nucleus of the thalamus for treatment of ET. DBS often reduces or eliminates the need for medications to treat ET. Proper patient selection and expertise in DBS programming are critical to ensure optimal outcomes. Recent advances in DBS include directional current steering and multisource independent constant current to program each electrode with its own power source. This chapter discusses proper patient selection, programming guidelines, and clinical pearls in DBS for ET.
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