药用植物抗鲍曼不动杆菌效果的系统综述研究

Current Chemical Biology Pub Date : 2022-12-08 DOI:10.2174/2212796817666221208115047

P. Shakib, A. Manouchehri, A. Marzban, H. Esmaeil Lashgarian, A. Alhameedawi

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引用次数: 0

摘要

鲍曼不动杆菌是一种机会性细菌，能够引起对多种抗生素耐药的医院感染。草药可能成为治疗耐抗生素细菌的新疗法的来源。本文综述了药用植物对鲍曼不动杆菌感染的治疗效果。通过系统检索PubMed、ISI Web of Science、Scopus、Science Direct、谷歌Scholar等数据库，以药用植物(包括提取物和精油)和细菌感染(包括鲍曼不对称杆菌)为特定关键词获取相关数据。本综述确定了2009年至2021年间发表的23项研究，这些研究讨论了药用植物抑制鲍曼不整虫生长的有效性。在这些研究中，发现28种药用植物在体内对鲍曼不动杆菌感染有效。本综述的结果表明，为了开发一种基于药用植物治疗细菌感染的治疗策略，特别是鲍曼不动杆菌，在将其作为抗生素的替代品之前，需要进行广泛的研究，以确定其细胞毒性和治疗剂量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A Systematic Review Study on the Effectiveness of Medicinal Plants against Acinetobacter baumannii

Acinetobacter baumannii is an opportunistic bacterium capable of causing nosocomial infections resistant to a wide range of antibiotics. Herbal medicines could become the source of novel therapies for antibiotic-resistant bacteria. This review paper aimed to survey the effectiveness of medicinal plants in treating infections caused by A. baumannii. The relevant data was obtained by systematically searching PubMed, ISI Web of Science, Scopus, Science Direct, and Google Scholar databases with the specific keywords of medicinal plants (including extracts and essential oils) and bacterial infections (including A. baumannii). The present review identified 23 studies published between 2009 and 2021 that discussed the effectiveness of medicinal plants in inhibiting the growth of A. baumannii. In these studies, 28 medicinal plants were found effective against infection caused by A. baumannii in vivo. The results of this review indicated that to develop a therapeutic strategy for treating bacterial infections, especially A. baumannii, based on medicinal plants, extensive studies were required to determine their cytotoxicity and therapeutic dosage before they could be used as an alternative to antibiotics.

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来源期刊

Current Chemical Biology Medicine-Biochemistry (medical)

CiteScore

1.40

自引率

0.00%

发文量

期刊介绍： Current Chemical Biology aims to publish full-length and mini reviews on exciting new developments at the chemistry-biology interface, covering topics relating to Chemical Synthesis, Science at Chemistry-Biology Interface and Chemical Mechanisms of Biological Systems. Current Chemical Biology covers the following areas: Chemical Synthesis (Syntheses of biologically important macromolecules including proteins, polypeptides, oligonucleotides, oligosaccharides etc.; Asymmetric synthesis; Combinatorial synthesis; Diversity-oriented synthesis; Template-directed synthesis; Biomimetic synthesis; Solid phase biomolecular synthesis; Synthesis of small biomolecules: amino acids, peptides, lipids, carbohydrates and nucleosides; and Natural product synthesis).