金属有机框架和共价有机框架作为光动力治疗的平台

IF 3.8 3区化学 Q1 CHEMISTRY, INORGANIC & NUCLEAR Comments on Inorganic Chemistry Pub Date : 2018-11-02 DOI:10.1080/02603594.2018.1542597

Yoshie Sakamaki, John Ozdemir, Zachary Heidrick, O. Watson, Hamid R. Shahsavari, Masood Fereidoonnezhad, A. Khosropour, Hassan Beyzavi

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引用次数: 22

摘要

我们描述了使用金属有机框架(MOFs)和共价有机框架(COFs)的最新光动力疗法(PDT)方法。PDT治疗癌症的特点是非侵入性和选择性的，引起了人们的广泛关注。PDT已经进入纳米技术领域，以克服各种阻碍其有效性的挑战。多孔材料比小分子功能更强，正在被探索作为PDT的平台。mof是这些研究的前沿，精心设计的纳米mof (nMOFs)的抗肿瘤能力最近已被报道。我们还讨论了在未来使用COFs进行PDT的可能性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Metal–Organic Frameworks and Covalent Organic Frameworks as Platforms for Photodynamic Therapy

We describe the newest approach to photodynamic therapy (PDT) using metal-organic frameworks (MOFs) and covalent organic frameworks (COFs). PDT’s characteristic method of treating cancer as noninvasive and selective has garnered much attention. PDT has entered the realm of nanotechnology to overcome various challenges that are hindering its effectiveness. Porous materials, which are more functional than small molecules, are being explored as platforms for PDT. MOFs are at the forefront of these investigations, and the anti-tumor ability of well-designed nano-MOFs (nMOFs) has recently been reported. We also discuss the possibility of using COFs for future-use PDT.

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来源期刊

Comments on Inorganic Chemistry 化学-无机化学与核化学

CiteScore

9.00

自引率

1.90%

发文量

审稿时长

>12 weeks

期刊介绍： Comments on Inorganic Chemistry is intended as a vehicle for authoritatively written critical discussions of inorganic chemistry research. We publish focused articles of any length that critique or comment upon new concepts, or which introduce new interpretations or developments of long-standing concepts. “Comments” may contain critical discussions of previously published work, or original research that critiques existing concepts or introduces novel concepts. Through the medium of “comments,” the Editors encourage authors in any area of inorganic chemistry - synthesis, structure, spectroscopy, kinetics and mechanisms, theory - to write about their interests in a manner that is both personal and pedagogical. Comments is an excellent platform for younger inorganic chemists whose research is not yet widely known to describe their work, and add to the spectrum of Comments’ author profiles, which includes many well-established inorganic chemists.