Saturated Halogenated Aliphatic Hydrocarbons Two to Four Carbons

This chapter relies extensively on information provided in earlier editions. Several online databases were utilized in searching for recent information in preparing the chapter. These included NTP (National Toxicology Program), IRIS (Integrated Risk Information Service), and the ATSDR (Agency for Toxic Substances and Disease Registry) websites. Most recent information was sought through MEDLINE and when possible the original articles were reviewed. Debatably, IRIS was considered to be the last word with regard to cancer. Many of the compounds have been recently reviewed by the ATSDR and are reported in their toxicological profiles. Recent reviews were utilized in preparing this chapter. In addition, the NIOSH Pocket Guide to Chemical Hazards and the ACGIH's TLV's® for Chemical Substances and Physical Agents: 2011 (CD) were utilized. Keywords: ethylene chloride; metabolic disposition; 1,1-dichloroethane; ethylene dichloride; methyl chloroform; 1,1,2-trichlorethane; 1,1,2,2-tetrachloroethane; pentachloroethane; hexachloroethane; propyl chloride; isopropyl chloride; ethyl bromide; ethylene dibromide; 1,1,2,2-tetrabromoethane