Methemoglobinemia in the postoperative period against the background of taking Almagel (clinical case)

Methemoglobinemia were recorded in two patients with intestinal paresis and gastrostasis in the early postoperative period and unauthorized intake of Almagel by patients for the relief of heartburn.In the presented cases, drugs that can cause methemoglobinemia were used in the treatment: ropivacaine, metoclopramide, ketoprofen. Nevertheless, taking into account the pairing of the presented cases, it is impossible to exclude the effect of the drug Almagel on methemoglobin genesis.CONCLUSION: the presented cases demonstrate manifestations of rare and poorly recognized drug methemoglobinemia, probably as a result of taking the antacid drug Almagel. Timely diagnosis and treatment of this condition ensures the rapid reversibility of a complex multifactorial biochemical process.