表明细胞基因组是读写存储器的数学和物理考虑

IF 3.2 3区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Progress in Biophysics & Molecular Biology Pub Date : 2023-03-01 DOI:10.1016/j.pbiomolbio.2023.01.006
Antonis Mistriotis
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引用次数: 1

摘要

到目前为止,控制生物进化的分子机制还没有完全阐明。最近的研究表明,调节蛋白作为决策的复杂装置,可以加速或延缓细胞的进化。这种生物化学控制的进化可以被认为是一种逻辑性质的优化过程,旨在培养更适合在特定环境中生存的物种。因此,我们可以假设,新的遗传信息可以通过复杂的生物分子过程存储在细胞存储器(即基因组)中,这类似于写入计算机存储器。最近的一项研究从理论上支持了这一假设,该研究表明,逻辑是生命的必要组成部分,因此生命系统以与计算机相同的方式处理信息。目前的研究总结了现有证据,表明细胞可以通过类似随机算法的生化过程有意修改其存储的数据,以避免环境压力并增加其生存机会。此外,还介绍了使读写存储器成为生物系统必要组成部分的数学和物理考虑因素。
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Mathematical and physical considerations indicating that the cell genome is a read-write memory

The molecular mechanisms that govern biological evolution have not been fully elucidated so far. Recent studies indicate that regulatory proteins, acting as decision-making complex devices, can accelerate or retard the evolution of cells. Such biochemically controlled evolution may be considered as an optimization process of logical nature aimed at developing fitter species that can better survive in a specific environment. Therefore, we may assume that new genetic information can be stored in the cell memory (i.e., genome) by a sophisticated biomolecular process that resembles writing in computer memory. Such a hypothesis is theoretically supported by a recent work showing that logic is a necessary component of life, so living systems process information in the same way as computers. The current study summarizes existing evidence showing that cells can intentionally modify their stored data by biochemical processes resembling stochastic algorithms to avoid environmental stress and increase their chances of survival. Furthermore, the mathematical and physical considerations that render a read-write memory a necessary component of biological systems are presented.

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来源期刊
Progress in Biophysics & Molecular Biology
Progress in Biophysics & Molecular Biology 生物-生化与分子生物学
CiteScore
8.60
自引率
7.90%
发文量
85
审稿时长
85 days
期刊介绍: Progress in Biophysics & Molecular Biology is an international review journal and covers the ground between the physical and biological sciences since its launch in 1950. It indicates to the physicist the great variety of unsolved problems awaiting attention in biology and medicine. The biologist and biochemist will find that this journal presents new and stimulating ideas and novel approaches to studying and influencing structural and functional properties of the living organism. This journal will be of particular interest to biophysicists, biologists, biochemists, cell physiologists, systems biologists, and molecular biologists.
期刊最新文献
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