加拿大COVID警报应用程序的流行病学影响

Shuo Sun, Mairead Shaw, E. Moodie, D. Ruths
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引用次数: 6

摘要

我们分析了加拿大COVID警报应用程序在减少COVID-19感染和因COVID-19病毒导致的死亡方面的有效性。采取了两种独立但互补的方法。首先,我们进行了一项比较研究,以评估与其他地区部署的类似应用程序相比,COVID警报应用程序的采用和使用情况。接下来,我们使用来自COVID警报服务器的数据和一系列合理的参数值,使用一个模型来估计加拿大避免的感染和死亡人数,该模型结合了通知数量、二次攻击率、可预防的传播的预期比例、隔离有效性以及在没有暴露通知的情况下整个传播链的预期规模等信息。对比分析显示,在报告使用情况的应用程序中,COVID Alert应用程序的采用率最低。我们的模型表明,在2021年3月至7月期间应用程序使用率最高的六个加拿大省份,COVID警报应用程序的使用避免了6284至10894例感染。这一范围相当于当时加拿大记录感染总数的1.6-2.9%。根据各省的病死率,在同一时期避免了57-101例死亡。安大略的病例和避免的死亡人数最多,而纽芬兰和拉布拉多的病例和避免的死亡比例最大。其他地区对应用程序影响措施的报告很少,也不一致,因此对影响的相对评估是不确定的。虽然全国范围内的比率较低,但广泛采用该应用程序的省份显示出较高的避免病例和死亡率(上限超过避免病例的60%)。这一发现表明,COVID警报应用程序如果得到充分采用,可以成为对抗COVID-19等大流行的有效公共卫生工具。
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The epidemiological impact of the Canadian COVID Alert app
We analyzed the effectiveness of the Canadian COVID Alert app on reducing COVID-19 infections and deaths due to the COVID-19 virus. Two separate but complementary approaches were taken. First, we undertook a comparative study to assess how the adoption and usage of the COVID Alert app compared to those of similar apps deployed in other regions. Next, we used data from the COVID Alert server and a range of plausible parameter values to estimate the numbers of infections and deaths averted in Canada using a model that combines information on number of notifications, secondary attack rate, expected fraction of transmissions that could be prevented, quarantine effectiveness, and expected size of the full transmission chain in the absence of exposure notification. The comparative analysis revealed that the COVID Alert app had among the lowest adoption levels among apps that reported usage. Our model indicates that use of the COVID Alert app averted between 6284 and 10,894 infections across the six Canadian provinces where app usage was highest during the March–July 2021 period. This range is equivalent to 1.6–2.9% of the total recorded infections across Canada in that time. Using province-specific case fatality rates, 57–101 deaths were averted during the same period. The number of cases and deaths averted was greatest in Ontario, whereas the proportion of cases and deaths averted was greatest in Newfoundland and Labrador. App impact measures were reported so rarely and so inconsistently by other regions that the relative assessment of impact is inconclusive. While the nationwide rates are low, provinces with widespread adoption of the app showed high ratios of averted cases and deaths (upper bound was greater than 60% of averted cases). This finding suggests that the COVID Alert app, when adopted at sufficient levels, can be an effective public health tool for combatting a pandemic such as COVID-19.
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Authors’ response: Re: Reifferscheid et al., “COVID-19 vaccine uptake and intention during pregnancy in Canada” Factors associated with intention to receive vaccines for bacterial sexually transmitted infections among young HPV-vaccinated Canadian women Re: Reifferscheid et al., “COVID-19 vaccine uptake and intention during pregnancy in Canada” Correction to: Convivialité des municipalités canadiennes à l’égard des aînés : portrait et facteurs associés Regional differences in movement behaviours of children and youth during the second wave of the COVID-19 pandemic in Canada: follow-up from a national study
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