中国减肥手术患者中阻塞性睡眠呼吸暂停的患病率及预测因素:一项单中心研究

Wenhui Chen, Xiaotao Zhang, Chetan Parmar, Yucheng Wang, Wah Yang, Jiyang Pan, Zhiyong Dong, Cunchuan Wang
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引用次数: 1

摘要

目的:本研究的目的是确定中国减肥手术患者的OSA患病率及其预测因素。材料与方法:收集326例接受减肥手术并接受多导睡眠图检查的患者的临床资料。采用多元logistic回归确定OSA存在的独立预测因子,并通过ROC曲线分析确定连续变量的最佳截断值。结果:基线BMI和年龄分别为33.3±3.7 kg/m2和24.3±3.1岁。62.9%的患者符合OSA诊断标准;其中,22.7%患有轻度OSA;11.3%为中度OSA, 28.8%为重度OSA。男性患病率(84.2%)明显高于女性(47.3%)(P2, 40.40 cm)。结论:我国减肥手术患者中OSA患病率较高(62.9%),其中男性患者患病率最高(84%)。年龄、BMI、颈围、是否存在习惯性打鼾和男性是这些患者OSA的独立预测因素。由于临床预测因素不足以成为OSA的适当筛查,应建议减肥手术候选人进行常规PSG检测。
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The Prevalence and Predictors of Obstructive Sleep Apnea in Chinese Bariatric Surgery Candidates: A Single-Center Study.

Purpose: The purpose of the study is to determine the prevalence and predictors of OSA in Chinese bariatric surgery candidates.

Materials and methods: The clinical data were collected from 326 patients evaluated for bariatric surgery and referred for polysomnography. Multiple logistic regression was used for identifying independent predictors of presence of OSA and ROC curve analysis to determine the best cut-off value for continuous variable.

Results: Baseline BMI and age were 33.3±3.7 kg/m2 and 24.3±3.1 years. 62.9% of the patients fulfilled the diagnostic criteria for OSA; Of these, 22.7% had mild OSA; 11.3% had moderate OSA, and 28.8% had severe OSA. The prevalence was significantly higher in males (84.2%) than in females (47.3%) (P<0.001). The superobese patients and the obese patients aged older than 50 years that all of those were diagnosed with OSA. A multivariate logistic regression model displayed that increasing age, BMI and neck circumference together with presence of habitual snoring and male sex were identified as risk factors of OSA. The best cut-off values for the presence of OSA for age, BMI, neck circumference were 24.5 years, 39.45 kg/m2, 40.40 cm.

Conclusion: The prevalence of OSA is very prevalent (62.9%) in Chinese bariatric surgery candidates, especially in male patients (84%). Age, BMI and neck circumference together with presence of habitual snoring and male sex are independent predictors of OSA in these patients. As clinical predictors are not enough to be a properly screening for OSA, routine PSG testing should be recommended to bariatric surgery candidates.

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