Svetlana Marija Goliškina, D. Cirule, Ē. Bizdēna, M. Turks
{"title":"Synthesis of 4-Alkylamino-2-Triazolylquinazolines","authors":"Svetlana Marija Goliškina, D. Cirule, Ē. Bizdēna, M. Turks","doi":"10.1515/msac-2017-0009","DOIUrl":null,"url":null,"abstract":"Abstract 5-Alkylamino derivatives of tetrazolo[1,5-a]quinazoline were obtained with high regioselectivity in the reaction of 5-azidotetrazolo[1,5-a]quinazoline (formally, 2,4-diazidoquinazoline) with long chain alkylamines. The obtained 5-aminoquinazoline derivatives were used in a copper catalyzed azide-alkyne 1,3-dipolar cycloaddition reaction to obtain series of 4-(alkylamino-2-(1,2,3-triazol-1-yl)quinazolines.","PeriodicalId":18239,"journal":{"name":"Materials Science and Applied Chemistry","volume":"5 1","pages":"59 - 62"},"PeriodicalIF":0.0000,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Materials Science and Applied Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1515/msac-2017-0009","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Abstract 5-Alkylamino derivatives of tetrazolo[1,5-a]quinazoline were obtained with high regioselectivity in the reaction of 5-azidotetrazolo[1,5-a]quinazoline (formally, 2,4-diazidoquinazoline) with long chain alkylamines. The obtained 5-aminoquinazoline derivatives were used in a copper catalyzed azide-alkyne 1,3-dipolar cycloaddition reaction to obtain series of 4-(alkylamino-2-(1,2,3-triazol-1-yl)quinazolines.
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