衰老的大脑:研究和实践的复杂挑战

IF 1.7 Q3 CLINICAL NEUROLOGY Aging brain Pub Date : 2023-01-01 DOI:10.1016/j.nbas.2022.100060
Josef Zihl , Simone Reppermund
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引用次数: 0

摘要

认知能力下降是智力老化的一部分,通常通过标准化测试进行评估;在这些测试中低于平均水平的表现被用作病理性认知老化的指标。此外,大脑的形态和功能变化被用作与年龄相关的认知能力病理性下降的参数。然而,认知变化的轨迹与大脑形态或功能变化之间并没有简单的联系。此外,低于平均水平的测试表现并不一定意味着日常活动中的重大损害。因此,从功能角度记录个人日常任务及其认知(和其他)需求显得至关重要。这也将允许对现有的和不充分的认知技能的生态有效性进行可靠的评估。理解和处理心理衰老的现象和后果当然不仅仅取决于认知。动机和情感以及个人的生活意义和生活满意度发挥着同样重要的作用。然而,这意味着认知只代表了心理衰老的一个方面,尽管它很重要。此外,创建和开发适当的功能认知评估工具是很重要的。在这篇文章中,我们想讨论一些我们认为与全面看待老龄化心理有关的方面,并促进加强多学科方法,包括与老龄化研究有关的所有基础科学和应用科学之间的密切合作,将研究结果快速转化为实践,以及所有学科和专业之间的密切合作,为老年人提供建议和支持。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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The aging mind: A complex challenge for research and practice

Cognitive decline as part of mental ageing is typically assessed with standardized tests; below-average performance in such tests is used as an indicator for pathological cognitive aging. In addition, morphological and functional changes in the brain are used as parameters for age-related pathological decline in cognitive abilities. However, there is no simple link between the trajectories of changes in cognition and morphological or functional changes in the brain. Furthermore, below-average test performance does not necessarily mean a significant impairment in everyday activities. It therefore appears crucial to record individual everyday tasks and their cognitive (and other) requirements in functional terms. This would also allow reliable assessment of the ecological validity of existing and insufficient cognitive skills. Understanding and dealing with the phenomena and consequences of mental aging does of course not only depend on cognition. Motivation and emotions as well personal meaning of life and life satisfaction play an equally important role. This means, however, that cognition represents only one, albeit important, aspect of mental aging. Furthermore, creating and development of proper assessment tools for functional cognition is important. In this contribution we would like to discuss some aspects that we consider relevant for a holistic view of the aging mind and promote a strengthening of a multidisciplinary approach with close cooperation between all basic and applied sciences involved in aging research, a quick translation of the research results into practice, and a close cooperation between all disciplines and professions who advise and support older people.

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Aging brain
Aging brain Neuroscience (General), Geriatrics and Gerontology
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