Optimal Patient Selection and Treatment Timing for Tolvaptan Therapy Following Cardiovascular Surgery - Reply.

predictor of the response to tolvaptan.6 In future, if possible, we would like to conduct a comparative study in a group of patients with poor renal function. However there is a high possibility that this group of patients will be treated with a combination of multiple drugs, such as other diuretics and carperitide, and it will therefore be difficult to evaluate the effects of tolvaptan alone.