从传统开放根治性膀胱切除术到腹腔镜根治性膀胱切除术对新膀胱的影响:回顾性研究

R. Shah, A. Trivedi, K. Rajyaguru, P. Bhatt
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引用次数: 0

摘要

背景:早期手术恢复和良好的生活质量是根治性膀胱切除术的重要目标。我们比较了开放式根治性膀胱切除术(ORC)和腹腔镜根治性膀胱切除术(LRC)治疗新膀胱的术前、围手术期和术后数据。患者与方法:回顾性分析13例连续由同一外科医生行根治性膀胱切除术的男性患者。所有患者均诊断为浸润性膀胱癌。腹部和术前分期采用计算机断层扫描。所有患者均未接受新辅助化疗。所有患者均行标准模板双侧盆腔淋巴结切除术。尿道改道包括原位新膀胱。所有患者在参与研究前均获得同意。结果:13例男性患者中,6例ORC合并新膀胱,7例行LRC手术。两组患者的基线特征(年龄、BMI、合并症、肿瘤分级、淋巴结状况)相似。与ORC组相比,LRC组的切口长度明显缩短(p <0.0001)。虽然LRC组的手术时间较ORC组长,但其镇痛时间缩短,住院时间缩短(p<0.05),以及立即拔除鼻胃管的液体摄入时间提前(p<0.001)。与ORC组不同,LRC组未观察到主要并发症,其中1例患者在30天死亡。结论:基于我们小样本研究的观察,LRC的围手术期和术后结果与ORC相比,对于接受新膀胱手术的患者来说,切口长度更小,疼痛和并发症更少,恢复更快,而不会危及肿瘤预后。由ORC向LRC过渡对患者有利。
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Impact of Transition from Conventional Open Radical Cystectomy to Laparoscopic Radical Cystectomy for Neobladder: A Retrospective Study
Background: Early operative recovery and good Quality of life are important goals of radical cystectomy. We compare the pre, peri and post operative data between Open radical cystectomy (ORC) and Laparoscopic radical cystectomy (LRC) surgery of neobladder. Patients and Methods: Retrospective analysis of 13 male consecutive patients who underwent radical cystectomy by a single surgeon was done. Diagnosis of all patients was of invasive bladder cancer. Abdominal and preoperative staging was done using computed tomography. None of them received neoadjuvant chemotherapy. All the patients received same standard template bilateral pelvic lympadenenectomy. The urinary diversion included orthotopic neobladder. All patients were consented prior to study participation. Results: Of the 13 male patients, six had ORC with neobladder while 7 underwent LRC surgery. Baseline characteristics (age, BMI, comorbidities, tumour grade, lymph node status) were similar in both groups. Incision length was significantly smaller in LRC as compared to ORC group (p <0.0001). Although the operative time was longer in LRC group as compared to ORC it was sufficed by reduced time for analgesics, shorter hospital stay (p<0.05), besides earlier time to liquid intake with immediate removal of nasogastric tube (p<0.001). No major complications were observed in the LRC unlike ORC group where one patient died at 30 days. Conclusions: Based on the observations of our small study sample peri and postoperative outcomes are promising for LRC compared to ORC for patients undergoing neobladder in terms of the smaller incision length associated with less pain and complications, with speedy recovery without jeopardizing oncological outcomes.Transition of surgeon from ORC to LRC was advantageous to patients.
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