Nathalie Jugnet, Michel Cosson, Armand Wattiez, Jacques Donnez, Valerie Buick, Gerard Mage, Demis Querleu
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Those patients with psychiatric histories, or with prolapses or stress incontinence which demanded surgery were excluded. Contraindications to any of the approaches (uterine volume larger than umbilicus, major previous pelvic surgery, severe endometriosis and virginity) were also considered to be exclusion criteria. A total of 82 patients who had undergone 31 vaginal hysterectomies, 31 total coelioscopic hysterectomies and 20 subtotal coelioscopic hysterectomies were followed up 1 year after the operation.</p><p>The population characteristics in the three groups were similar. Operating times were 70.8 min for vaginal hysterectomies (VH), 67.6 min for total percoelioscopic hysterectomies (TPCH) and 111.5 min for subtotal percoelioscopic hysterectomies (SPCH). The mean hospital stay was comparable in the three groups. The mean uterine weight was 225 g for the VH group, 281 g for the TPCH and 206.5 g for the SPCH group (<i>P</i> was not significant). The pain evaluation scales used by the patients during their hospital stay did not show any significant difference between the three groups. The mean times before patients could walk, return to work or resume sexual intercourse showed no significant differences between the groups. Mild urinary signs were reported in the mid-term without any significant difference. Physical activity improved in 38.7% of the patients who had undergone VH, in 46.6% who had undergone TPCH and in 60% who had undergone SPCH (<i>P</i> not significant). Those patients who had undergone SPCH resumed satisfactory sexual intercourse significantly earlier (<i>P</i> = 0.0002). Intercourse was not significantly modified in the three groups. Quality of life was generally and significantly improved for 80.6%, 96.5% and 70%, respectively, of the patients in the VH, TPCH and SPCH groups.</p><p>Although some surgical teams are still reluctant to practise coelioscopic hysterectomies, all three hysterectomy types were finally demonstrated to be equivalent in this study. They were proved to be feasible even in patients with a large uterus. 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引用次数: 8
摘要
三个外科单位参与了一项前瞻性比较研究:法国鲁贝的Pavillon Paul gell阴道子宫切除术;法国Clermont-Ferrand的Hôtel Dieu Polyclinic进行全腔镜子宫切除术;比利时布鲁塞尔的Saint-Luc诊所进行子宫次全腔镜切除术。纳入标准为年龄(38-55岁),未绝经或接受过更年期替代治疗,有轻度子宫病理伴或不伴去势体征,但无盆腔疼痛。阴道或腹腔镜入路必须可行。那些有精神病史,或有脱垂或压力性尿失禁需要手术的患者被排除在外。任何入路的禁忌症(子宫体积大于脐部,既往盆腔手术,严重子宫内膜异位症和童贞)也被认为是排除标准。82例经阴道子宫切除术31例,全腔镜子宫切除术31例,次全腔镜子宫切除术20例,术后随访1年。三组人群特征相似。阴道子宫切除术(VH)的手术时间为70.8 min,全腔镜子宫切除术(TPCH)的手术时间为67.6 min,次全腔镜子宫切除术(SPCH)的手术时间为111.5 min。三组的平均住院时间具有可比性。VH组平均子宫重量为225 g, TPCH组为281 g, SPCH组为206.5 g (P无统计学意义)。患者在住院期间使用的疼痛评估量表在三组间无显著差异。患者能够行走、恢复工作或恢复性生活的平均时间在两组之间没有显著差异。中期出现轻度尿路体征,差异无统计学意义。VH组38.7%、TPCH组46.6%、SPCH组60%的患者体力活动改善(P无统计学意义)。行SPCH者性生活恢复满意的时间明显早于行SPCH者(P = 0.0002)。三组的性交没有明显改变。VH组、TPCH组和SPCH组患者的生活质量分别有80.6%、96.5%和70%的患者普遍改善和显著改善。尽管一些外科团队仍然不愿意进行腔镜子宫切除术,但在本研究中,所有三种子宫切除术类型最终被证明是等效的。它们被证明是可行的,甚至在患者的大子宫。手术时间不再是不利因素,当肠镜检查是由高度熟练的外科医生进行。
Comparing vaginal and coelioscopic total or subtotal hysterectomies: prospective multicentre study including 82 patients
Three surgical units were involved in a prospective comparative study: the Pavillon Paul Gellé in Roubaix, France for vaginal hysterectomies; the Hôtel Dieu Polyclinic in Clermont-Ferrand, France for total percoelioscopic hysterectomies; and the Saint-Luc Clinic in Brussels, Belgium for subtotal percoelioscopic hysterectomies.
The inclusion criteria were age (38–55 years old), the patients were either not menopausal or else they had received alternative therapies for menopause, and had mild uterine pathology with or without castration signs, but without pelvic pain. The vaginal or coelioscopic approach had to be practicable. Those patients with psychiatric histories, or with prolapses or stress incontinence which demanded surgery were excluded. Contraindications to any of the approaches (uterine volume larger than umbilicus, major previous pelvic surgery, severe endometriosis and virginity) were also considered to be exclusion criteria. A total of 82 patients who had undergone 31 vaginal hysterectomies, 31 total coelioscopic hysterectomies and 20 subtotal coelioscopic hysterectomies were followed up 1 year after the operation.
The population characteristics in the three groups were similar. Operating times were 70.8 min for vaginal hysterectomies (VH), 67.6 min for total percoelioscopic hysterectomies (TPCH) and 111.5 min for subtotal percoelioscopic hysterectomies (SPCH). The mean hospital stay was comparable in the three groups. The mean uterine weight was 225 g for the VH group, 281 g for the TPCH and 206.5 g for the SPCH group (P was not significant). The pain evaluation scales used by the patients during their hospital stay did not show any significant difference between the three groups. The mean times before patients could walk, return to work or resume sexual intercourse showed no significant differences between the groups. Mild urinary signs were reported in the mid-term without any significant difference. Physical activity improved in 38.7% of the patients who had undergone VH, in 46.6% who had undergone TPCH and in 60% who had undergone SPCH (P not significant). Those patients who had undergone SPCH resumed satisfactory sexual intercourse significantly earlier (P = 0.0002). Intercourse was not significantly modified in the three groups. Quality of life was generally and significantly improved for 80.6%, 96.5% and 70%, respectively, of the patients in the VH, TPCH and SPCH groups.
Although some surgical teams are still reluctant to practise coelioscopic hysterectomies, all three hysterectomy types were finally demonstrated to be equivalent in this study. They were proved to be feasible even in patients with a large uterus. Operating times are no longer unfavourable factors when coelioscopies are performed by highly skilled surgeons.