生物医学用手混pmma基水泥的性能研究

F. Živić, N. Grujovic, S. Pelemiš, D. Adamović
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摘要

本文介绍了PMMA骨水泥的最新发展趋势,并考虑了其在临床应用中的改进。对手工混合PMMA骨水泥进行了实验研究,旨在确定材料在纳米压痕过程中的力学行为。采用标准的多循环压痕试验,最大载荷为15牛,载荷立即松弛至5牛,使用锋利的维氏压头。得到了三种不同循环次数(100次、200次和300次)和试样表面不同压痕位置的压痕曲线,并分析了压痕曲线作为法向载荷与渗透深度的函数。从最终材料结构及其后续力学行为的角度对产生的压痕进行了分析。在最终硬化的水泥中,在某些表面区域观察到PMMA微珠的结块,表明材料结构不均匀。循环次数的变化对试样的力学响应无显著影响。然而,PMMA微球聚集的部位呈现出明显不同的压痕曲线,这表明手工混合PMMA骨水泥会产生不均匀的最终材料结构。
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PROPERTIES OF THE HAND MIXED PMMA BASED CEMENT FOR BIOMEDICAL APPLICATIONS
This paper presents insights into the recent trends in development of PMMA bone cements considering their improvements for applications in clinical practice. Experimental investigation of hand mixed PMMA bone cement was realized, aiming to determine mechanical behavior of the material during nanoindentation. Standard multi-cycle indentation tests were applied, with maximum load of 15 N and immediate load relaxation down to 5 N, with sharp Vickers indenter. Indentation curves were obtained and analyzed as the function of the normal load vs penetration depth, for three different numbers of cycles (100, 200 and 300 cycles) and different indentation positions on the sample surface. Resulting indents were analyses from the aspect of the final material structure and its subsequent mechanical behavior. Agglomeration of PMMA beads was observed in the final hardened cement in some surface zones, thus indicating non-homogenous material structure. Changes in the number of cycles did not show significant influence on the mechanical response of the sample. However, sites with agglomerated PMMA beads showed significantly different indentation curves, thus indicating that hand-mixing of PMMA bone cement can produce non-homogenous final material structure.
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