甜菜根提取物调节贫血大鼠缺铁性贫血的疗效评价

Z. A. Ali, A.Bilal
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摘要

目的:比较甜菜根提取物和铁补充剂(Iberet Folic)对缺铁贫血大鼠铁和血红蛋白水平的影响。方法:在本研究中,将天然铁源、甜菜根提取物和铁补充剂(Iberetfolic)给予苯肼诱导的贫血大鼠21天。首先将甜菜根干燥,制成粉末,然后用乙醇提取。结果:本实验中甜菜根对血红蛋白、红细胞和铁血清的改善作用,平均值分别为23.8±0.69 g/dL、15.16±0.54 106 /μL和31.5±1.5 μ dL。与甜菜根相比,补铁的贫血大鼠血红蛋白、红细胞和血清铁的平均值变化较小;分别为(22.4±0.443)g/dL、(13.69±0.5106)g/dL、(30.1±0.9)g/dL。结论:本研究中甜菜根提取物可作为常规局部补铁剂的可行替代品。
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EFFICACY ASSESSMENT OF BEETROOT EXTRACT IN REGULATING IRON DEFICIENCY ANEMIA IN ANEMIC RATS
Objective: Comparison of beetroot extract and iron supplement (Iberet Folic) effects on iron andhaemoglobin levels among iron deficient anaemic rats.Methodology: In this study a natural source of iron, beetroot extract, and iron supplement (Iberetfolic) was administrated to phenyl-hydrazine induced anaemic rats for 21 days. Beetroot was firstdried, powdered, then extracted by ethanol.Results: The beetroot in current experimental study showed improvements in haemoglobin, red bloodcells, and iron serum as mean values of 23.8±0.69 g/dL, 15.16 ±0.54 106 /μL, and 31.5 ±1.5 μg/dL,respectively. As compared to beetroot, minor changes could be seen in mean values of haemoglobin,red blood cells, and serum iron of iron supplemented anaemic rats as; 22.4 ±0.443 g/dL, 13.69 ±0.5106 /μL, and 30.1 ±0.9 μg/dL, correspondingly.Conclusion: The Beetroot extract in this study presented as a viable replacement to the conventionallocal iron supplement.
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