海洋天然产物:新一代药物疗法

R. Goel, Binny Mahendru, T. Saini
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引用次数: 0

摘要

尽管海洋覆盖了地球表面的四分之三,而且地球上的生命起源于海洋,但迄今为止,海洋的生物医学潜力在很大程度上尚未得到开发。然而,随着专业深海潜水员的到来,海洋研究人员可以接触到各种海洋生物,如海绵、珊瑚、海胆、海鞘、水螅、海葵、鱼类和软体动物,以及各种海洋植物,包括藻类和其他嵌入海床的微生物。生物医学科学家们正在利用这些资源来提取具有药理特性的海洋天然产品(MNPs),有朝一日可能治愈从细菌感染到癌症、阿尔茨海默氏症和艾滋病等一系列疾病,这是这篇综述文章的重点。
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Marine natural products: the new generation of pharmacotherapeutics
The biomedical potential of the sea has gone largely unexplored so far, despite the fact that it covers three quarters of the planet surface and the fact that life on Earth originated from the sea. However, with the arrival of the professional deep sea divers, the marine researchers have gained access to all sorts of marine creatures like sponges, corals, sea urchins, sea squirts, hydroids, sea anemones, fishes and mollusks as well as to varied types of sea plants including algae and the other micro-organisms embedded in the sea bed. The biomedical scientists are exploiting these all to extract marine natural products (MNPs) having pharmacological properties that may one day cure long list of illnesses varying from bacterial infections to cancer, Alzheimer's and AIDS and was the focus of this review article.
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