通过检测热效应突破红外显微镜衍射极限

2017 IEEE Photonics Conference (IPC) Part II Pub Date : 2017-10-01 DOI:10.1109/IPCON.2017.8115977

Delong Zhang, Ji‐Xin Cheng

{"title":"通过检测热效应突破红外显微镜衍射极限","authors":"Delong Zhang, Ji‐Xin Cheng","doi":"10.1109/IPCON.2017.8115977","DOIUrl":null,"url":null,"abstract":"We report a mid-infrared photothermal microscope with sub-micron spatial resolution. Such performance has exceeded the diffraction limit of infrared microscopy and allowed label-free three-dimensional chemical imaging of live cells and organisms. Distributions of endogenous lipid and exogenous drug inside single cells were visualized.","PeriodicalId":6657,"journal":{"name":"2017 IEEE Photonics Conference (IPC) Part II","volume":"47 S221","pages":"1-2"},"PeriodicalIF":0.0000,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Beating the diffraction limit in IR microscopy through detecting the thermal effect\",\"authors\":\"Delong Zhang, Ji‐Xin Cheng\",\"doi\":\"10.1109/IPCON.2017.8115977\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We report a mid-infrared photothermal microscope with sub-micron spatial resolution. Such performance has exceeded the diffraction limit of infrared microscopy and allowed label-free three-dimensional chemical imaging of live cells and organisms. Distributions of endogenous lipid and exogenous drug inside single cells were visualized.\",\"PeriodicalId\":6657,\"journal\":{\"name\":\"2017 IEEE Photonics Conference (IPC) Part II\",\"volume\":\"47 S221\",\"pages\":\"1-2\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2017 IEEE Photonics Conference (IPC) Part II\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/IPCON.2017.8115977\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2017 IEEE Photonics Conference (IPC) Part II","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IPCON.2017.8115977","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

我们报道了一种亚微米空间分辨率的中红外光热显微镜。这样的性能已经超过了红外显微镜的衍射极限，并允许活细胞和生物体的无标记三维化学成像。观察内源性脂质和外源性药物在单细胞内的分布。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Beating the diffraction limit in IR microscopy through detecting the thermal effect

We report a mid-infrared photothermal microscope with sub-micron spatial resolution. Such performance has exceeded the diffraction limit of infrared microscopy and allowed label-free three-dimensional chemical imaging of live cells and organisms. Distributions of endogenous lipid and exogenous drug inside single cells were visualized.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

2017 IEEE Photonics Conference (IPC) Part II

自引率

0.00%

发文量