{"title":"潜在心力衰竭对COVID-19预后的影响系统回顾和荟萃分析。","authors":"Soroush Morsali, Erfan Rezazadeh-Gavgani, Mobina Oladghaffari, Shirin Bahramian, Sina Hamzehzadeh, Zahra Samadifar, Elgar Enamzadeh, Zahra Sheikhalipour, Haniyeh Moradi, Hanieh Salehi Pourmehr, Amirreza Naseri, Mohammadreza Taban-Sadeghi, Sara Daneshvar","doi":"10.2478/rjim-2022-0021","DOIUrl":null,"url":null,"abstract":"<p><p><b>Background:</b> The risk for worse outcomes of COVID-19 (Coronavirus 2019 disease) is higher in patients with cardiac conditions. In this study, we aim to investigate the risks of COVID-19-induced conditions in cases with underlying heart failure. <b>Methods:</b> We systematically searched PubMed, Scopus, Ovid, ProQuest, Web of Science, and the Cochrane library, to collect the English language articles that investigated patients with underlying heart failure who get infected by COVID-19. The second version of comprehensive meta-analysis (CMA.2) software was used to conduct the meta-analysis. <b>Results:</b> From 5997 publications, our eligibility criteria were met by 27 studies. Overall, outcomes investigated in all studies include but are not limited to mortality rate, length of hospitalization, need for Intensive care unit (ICU) admission, need for mechanical ventilation, and major cardiovascular conditions. Regarding mortality heart failure patients were more susceptible to death (OR:2.570, 95%CI: 2.085 to 3.169; p-value:<0.001). Also in heart failure patients, the risk of mechanical ventilation was higher (OR:1.707, 95%CI: 1.113 to 2.617; p-value: 0.014). <b>Conclusion:</b> Pre-existing heart failure is associated with the increased risk of mortality and the need for mechanical ventilation while getting infected with COVID-19. Finding an answer to determine the risk of hospitalization, length of stay, readmission rate, and multiorgan failure is necessary for further development of preventive care and making a plan for providing optimal healthcare facilities for these patients.</p>","PeriodicalId":21463,"journal":{"name":"Romanian Journal of Internal Medicine","volume":null,"pages":null},"PeriodicalIF":1.6000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Effects of underlying heart failure on outcomes of COVID-19; a systematic review and meta-analysis.\",\"authors\":\"Soroush Morsali, Erfan Rezazadeh-Gavgani, Mobina Oladghaffari, Shirin Bahramian, Sina Hamzehzadeh, Zahra Samadifar, Elgar Enamzadeh, Zahra Sheikhalipour, Haniyeh Moradi, Hanieh Salehi Pourmehr, Amirreza Naseri, Mohammadreza Taban-Sadeghi, Sara Daneshvar\",\"doi\":\"10.2478/rjim-2022-0021\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Background:</b> The risk for worse outcomes of COVID-19 (Coronavirus 2019 disease) is higher in patients with cardiac conditions. In this study, we aim to investigate the risks of COVID-19-induced conditions in cases with underlying heart failure. <b>Methods:</b> We systematically searched PubMed, Scopus, Ovid, ProQuest, Web of Science, and the Cochrane library, to collect the English language articles that investigated patients with underlying heart failure who get infected by COVID-19. The second version of comprehensive meta-analysis (CMA.2) software was used to conduct the meta-analysis. <b>Results:</b> From 5997 publications, our eligibility criteria were met by 27 studies. Overall, outcomes investigated in all studies include but are not limited to mortality rate, length of hospitalization, need for Intensive care unit (ICU) admission, need for mechanical ventilation, and major cardiovascular conditions. Regarding mortality heart failure patients were more susceptible to death (OR:2.570, 95%CI: 2.085 to 3.169; p-value:<0.001). Also in heart failure patients, the risk of mechanical ventilation was higher (OR:1.707, 95%CI: 1.113 to 2.617; p-value: 0.014). <b>Conclusion:</b> Pre-existing heart failure is associated with the increased risk of mortality and the need for mechanical ventilation while getting infected with COVID-19. Finding an answer to determine the risk of hospitalization, length of stay, readmission rate, and multiorgan failure is necessary for further development of preventive care and making a plan for providing optimal healthcare facilities for these patients.</p>\",\"PeriodicalId\":21463,\"journal\":{\"name\":\"Romanian Journal of Internal Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2023-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Romanian Journal of Internal Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2478/rjim-2022-0021\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Romanian Journal of Internal Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2478/rjim-2022-0021","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 1
摘要
背景:患有心脏疾病的患者发生COVID-19(冠状病毒2019疾病)不良结局的风险更高。在这项研究中,我们的目的是调查潜在心力衰竭病例中covid -19诱发疾病的风险。方法:系统检索PubMed、Scopus、Ovid、ProQuest、Web of Science、Cochrane图书馆,收集调查新型冠状病毒感染的潜在心力衰竭患者的英文文章。采用第二版综合meta分析(CMA.2)软件进行meta分析。结果:在5997篇出版物中,有27篇研究符合我们的入选标准。总体而言,所有研究调查的结果包括但不限于死亡率、住院时间、重症监护病房(ICU)入院需求、机械通气需求和主要心血管疾病。在死亡率方面,心力衰竭患者更容易死亡(OR:2.570, 95%CI: 2.085 ~ 3.169;结论:既往心力衰竭与COVID-19感染时死亡风险增加和机械通气需求增加有关。找到确定住院风险、住院时间、再入院率和多器官衰竭的答案,对于进一步发展预防保健和制定为这些患者提供最佳医疗保健设施的计划是必要的。
Effects of underlying heart failure on outcomes of COVID-19; a systematic review and meta-analysis.
Background: The risk for worse outcomes of COVID-19 (Coronavirus 2019 disease) is higher in patients with cardiac conditions. In this study, we aim to investigate the risks of COVID-19-induced conditions in cases with underlying heart failure. Methods: We systematically searched PubMed, Scopus, Ovid, ProQuest, Web of Science, and the Cochrane library, to collect the English language articles that investigated patients with underlying heart failure who get infected by COVID-19. The second version of comprehensive meta-analysis (CMA.2) software was used to conduct the meta-analysis. Results: From 5997 publications, our eligibility criteria were met by 27 studies. Overall, outcomes investigated in all studies include but are not limited to mortality rate, length of hospitalization, need for Intensive care unit (ICU) admission, need for mechanical ventilation, and major cardiovascular conditions. Regarding mortality heart failure patients were more susceptible to death (OR:2.570, 95%CI: 2.085 to 3.169; p-value:<0.001). Also in heart failure patients, the risk of mechanical ventilation was higher (OR:1.707, 95%CI: 1.113 to 2.617; p-value: 0.014). Conclusion: Pre-existing heart failure is associated with the increased risk of mortality and the need for mechanical ventilation while getting infected with COVID-19. Finding an answer to determine the risk of hospitalization, length of stay, readmission rate, and multiorgan failure is necessary for further development of preventive care and making a plan for providing optimal healthcare facilities for these patients.