Koichi Ito, Jack Carter, V. Thodima, Youyou Zhang, Monisha Sivakumar, Mu Xu, N. Bhagwat, J. Rager, Jacob Spruance, Lin Zhang, Bruce R Ruggeri, P. Scherle, K. Vaddi
{"title":"摘要:PRMT5抑制在表观遗传学上调控癌细胞的DNA损伤反应途径,并对化疗和PARP抑制增敏","authors":"Koichi Ito, Jack Carter, V. Thodima, Youyou Zhang, Monisha Sivakumar, Mu Xu, N. Bhagwat, J. Rager, Jacob Spruance, Lin Zhang, Bruce R Ruggeri, P. Scherle, K. Vaddi","doi":"10.1158/1538-7445.AM2021-1185","DOIUrl":null,"url":null,"abstract":"","PeriodicalId":12258,"journal":{"name":"Experimental and Molecular Therapeutics","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Abstract 1185: PRMT5 inhibition epigenetically regulates DNA damage response pathways in cancer cells and sensitizes to chemotherapy and PARP inhibition\",\"authors\":\"Koichi Ito, Jack Carter, V. Thodima, Youyou Zhang, Monisha Sivakumar, Mu Xu, N. Bhagwat, J. Rager, Jacob Spruance, Lin Zhang, Bruce R Ruggeri, P. Scherle, K. Vaddi\",\"doi\":\"10.1158/1538-7445.AM2021-1185\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\",\"PeriodicalId\":12258,\"journal\":{\"name\":\"Experimental and Molecular Therapeutics\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Experimental and Molecular Therapeutics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1158/1538-7445.AM2021-1185\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Experimental and Molecular Therapeutics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1158/1538-7445.AM2021-1185","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Abstract 1185: PRMT5 inhibition epigenetically regulates DNA damage response pathways in cancer cells and sensitizes to chemotherapy and PARP inhibition