不良妊娠结局与实验室测量作为心血管疾病风险之间的关系

Haneen Hussein Farhood, Manal Khalid Abdulridha, Hameedah Hadi
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引用次数: 0

摘要

背景;由于心血管疾病的病因复杂,全面的风险评估是必要的筛查原因。许多已发表的研究将妊娠并发症与未来心血管疾病(CVD)风险联系起来。客观的;探讨实验室测量的危险因素和不良妊娠结局(APOs)与心血管疾病风险水平之间的关系。方法;成年女性参加了一项横断面研究,根据她们是否有不良妊娠结局的历史将她们分为两组。进行实验室和临床测量,并根据Framingham风险评分计算CVD风险。结果;所有参与研究的女性年龄都在40岁以上,大多肥胖,主要是A+ve和O+ve血型表型。与低风险组相比,有妊娠高血压和先兆子痫阳性病史的妇女处于中间组的可能性是7.5倍,而有死产阳性病史的妇女处于高危组的可能性是17.2倍。结论;在低风险类别中,妊娠高血压和先兆子痫阳性史是中度CVD风险的预测因子,而死产阳性史是高CVD风险的预测因子。
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The Association between Adverse Pregnancy Outcomes and Laboratory Measures as Risk for Cardiovascular Disorders
Background; Due to the complicated etiology of cardiovascular illnesses, a thorough risk assessment is necessary for screening reasons. Many published studies relate the pregnancy complications and future cardiovascular disease (CVD) risk. Objective; Investigate the association between risk factors of the laboratory measures and adverse pregnancy outcomes (APOs) with level of cardiovascular disorders risk. Methods; Adult women were enrolled in a cross-sectional study, and they were divided into 2 groups according to whether they had a history of adverse pregnancy outcomes or not. Laboratory and clinical measurements were carried out, and The CVD risk was calculated according to Framingham risk score. Results; All women enrolled were over 40 years age, mostly obese, had predominantly A+ve and O+ve blood group phenotypes. As compared to the low risk category, women with a positive history of pregnancy-induced hypertension and preeclampsia were 7.5 times more likely to be in the intermediate group while those with a positive history of stillbirth were 17.2 times more likely to be in the high-risk group. Conclusion; With reference to the low risk category, a positive history of pregnancy-induced hypertension and preeclampsia was predictor for intermediate CVD risk, while a positive history of stillbirth was predictor for high CVD risk.
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